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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMD3 All Species: 23.94
Human Site: S105 Identified Species: 40.51
UniProt: O43242 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43242 NP_002800.2 534 60978 S105 L R M L P S T S R R L N H Y V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094505 534 60977 S105 L R M L P S T S R R L N H Y V
Dog Lupus familis XP_548138 534 60948 S105 L R M L P S T S R R L N H Y V
Cat Felis silvestris
Mouse Mus musculus P14685 530 60681 S101 L R M L P S T S R R L N H Y V
Rat Rattus norvegicus NP_001008282 530 60670 S101 L R M L P S T S R R L N H Y V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026533 519 59378 S90 L R A L P S T S R R L N A N V
Frog Xenopus laevis NP_001085955 498 57453 F84 V H K A I N G F F T S N P T T
Zebra Danio Brachydanio rerio NP_956866 503 57904 L82 R R L N T N V L H K A V S G F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25161 494 55986 Q81 V V F R N L A Q S I Y P A G A
Honey Bee Apis mellifera XP_623947 495 56922 G81 L N S N V L R G V I L S L Y S
Nematode Worm Caenorhab. elegans Q04908 504 57488 S82 K L V S S H L S S D A Q F A E
Sea Urchin Strong. purpuratus XP_784007 501 57553 Y88 L R K L I S G Y I P N G N T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LNU4 488 55564 R83 P G S E A H S R L S S F V P K
Baker's Yeast Sacchar. cerevisiae P40016 523 60404 F88 L Y P D S S S F K K N L L K F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.4 98.1 N.A. 97.1 97.1 N.A. N.A. 88.3 82.7 82 N.A. 55.4 58.4 39.7 65.3
Protein Similarity: 100 N.A. 99.6 98.5 N.A. 97.7 97.7 N.A. N.A. 92.3 87 88.3 N.A. 70.5 72.8 58.2 78.8
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 80 6.6 6.6 N.A. 0 20 6.6 26.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 80 20 26.6 N.A. 6.6 26.6 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 43.2 31.4 N.A.
Protein Similarity: N.A. N.A. N.A. 60.6 55.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 8 0 8 0 0 0 15 0 15 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 8 0 0 0 0 15 8 0 0 8 8 0 15 % F
% Gly: 0 8 0 0 0 0 15 8 0 0 0 8 0 15 0 % G
% His: 0 8 0 0 0 15 0 0 8 0 0 0 36 0 0 % H
% Ile: 0 0 0 0 15 0 0 0 8 15 0 0 0 0 0 % I
% Lys: 8 0 15 0 0 0 0 0 8 15 0 0 0 8 8 % K
% Leu: 65 8 8 50 0 15 8 8 8 0 50 8 15 0 0 % L
% Met: 0 0 36 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 15 8 15 0 0 0 0 15 50 8 8 0 % N
% Pro: 8 0 8 0 43 0 0 0 0 8 0 8 8 8 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % Q
% Arg: 8 58 0 8 0 0 8 8 43 43 0 0 0 0 0 % R
% Ser: 0 0 15 8 15 58 15 50 15 8 15 8 8 0 15 % S
% Thr: 0 0 0 0 8 0 43 0 0 8 0 0 0 15 8 % T
% Val: 15 8 8 0 8 0 8 0 8 0 0 8 8 0 43 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 8 0 0 8 0 0 43 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _