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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMD3
All Species:
25.45
Human Site:
S272
Identified Species:
43.08
UniProt:
O43242
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43242
NP_002800.2
534
60978
S272
D
Q
A
E
K
L
V
S
K
S
V
F
P
E
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094505
534
60977
S272
D
Q
A
E
K
L
V
S
K
S
V
F
P
E
Q
Dog
Lupus familis
XP_548138
534
60948
S272
D
Q
A
E
K
L
V
S
K
S
V
F
P
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
P14685
530
60681
S268
D
Q
A
E
K
L
V
S
K
S
V
F
P
E
Q
Rat
Rattus norvegicus
NP_001008282
530
60670
S268
D
Q
A
E
K
L
V
S
K
S
V
F
P
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026533
519
59378
S257
D
Q
A
E
K
L
V
S
K
S
V
F
P
E
Q
Frog
Xenopus laevis
NP_001085955
498
57453
R251
A
N
N
N
E
W
A
R
Y
L
Y
Y
T
G
R
Zebra Danio
Brachydanio rerio
NP_956866
503
57904
A249
K
S
V
F
P
E
L
A
N
N
N
E
W
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25161
494
55986
R248
A
S
N
N
E
W
A
R
F
L
Y
Y
L
G
R
Honey Bee
Apis mellifera
XP_623947
495
56922
R248
A
S
N
N
E
W
A
R
F
L
Y
Y
L
G
R
Nematode Worm
Caenorhab. elegans
Q04908
504
57488
S249
V
A
F
P
D
N
A
S
N
N
D
L
A
R
Y
Sea Urchin
Strong. purpuratus
XP_784007
501
57553
R255
A
S
N
H
E
W
A
R
F
L
Y
Y
L
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LNU4
488
55564
R250
L
F
Y
L
G
K
I
R
T
I
Q
L
E
Y
T
Baker's Yeast
Sacchar. cerevisiae
P40016
523
60404
S255
D
S
A
S
D
F
I
S
K
L
E
Y
P
H
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.4
98.1
N.A.
97.1
97.1
N.A.
N.A.
88.3
82.7
82
N.A.
55.4
58.4
39.7
65.3
Protein Similarity:
100
N.A.
99.6
98.5
N.A.
97.7
97.7
N.A.
N.A.
92.3
87
88.3
N.A.
70.5
72.8
58.2
78.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
0
0
N.A.
0
0
6.6
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
20
26.6
N.A.
20
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.2
31.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.6
55.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
8
50
0
0
0
36
8
0
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
15
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
43
29
8
0
0
0
0
8
8
8
43
0
% E
% Phe:
0
8
8
8
0
8
0
0
22
0
0
43
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
29
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
15
0
0
8
0
0
0
0
0
% I
% Lys:
8
0
0
0
43
8
0
0
50
0
0
0
0
0
0
% K
% Leu:
8
0
0
8
0
43
8
0
0
36
0
15
22
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
29
22
0
8
0
0
15
15
8
0
0
0
0
% N
% Pro:
0
0
0
8
8
0
0
0
0
0
0
0
50
0
0
% P
% Gln:
0
43
0
0
0
0
0
0
0
0
8
0
0
0
43
% Q
% Arg:
0
0
0
0
0
0
0
36
0
0
0
0
0
8
36
% R
% Ser:
0
36
0
8
0
0
0
58
0
43
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
15
% T
% Val:
8
0
8
0
0
0
43
0
0
0
43
0
0
0
0
% V
% Trp:
0
0
0
0
0
29
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
8
0
29
36
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _