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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMD3
All Species:
22.73
Human Site:
S274
Identified Species:
38.46
UniProt:
O43242
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43242
NP_002800.2
534
60978
S274
A
E
K
L
V
S
K
S
V
F
P
E
Q
A
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094505
534
60977
S274
A
E
K
L
V
S
K
S
V
F
P
E
Q
A
N
Dog
Lupus familis
XP_548138
534
60948
S274
A
E
K
L
V
S
K
S
V
F
P
E
Q
A
N
Cat
Felis silvestris
Mouse
Mus musculus
P14685
530
60681
S270
A
E
K
L
V
S
K
S
V
F
P
E
Q
A
N
Rat
Rattus norvegicus
NP_001008282
530
60670
S270
A
E
K
L
V
S
K
S
V
F
P
E
Q
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026533
519
59378
S259
A
E
K
L
V
S
K
S
V
F
P
E
Q
A
N
Frog
Xenopus laevis
NP_001085955
498
57453
L253
N
N
E
W
A
R
Y
L
Y
Y
T
G
R
I
K
Zebra Danio
Brachydanio rerio
NP_956866
503
57904
N251
V
F
P
E
L
A
N
N
N
E
W
A
R
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25161
494
55986
L250
N
N
E
W
A
R
F
L
Y
Y
L
G
R
I
K
Honey Bee
Apis mellifera
XP_623947
495
56922
L250
N
N
E
W
A
R
F
L
Y
Y
L
G
R
I
K
Nematode Worm
Caenorhab. elegans
Q04908
504
57488
N251
F
P
D
N
A
S
N
N
D
L
A
R
Y
M
Y
Sea Urchin
Strong. purpuratus
XP_784007
501
57553
L257
N
H
E
W
A
R
F
L
Y
Y
L
G
R
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LNU4
488
55564
I252
Y
L
G
K
I
R
T
I
Q
L
E
Y
T
D
A
Baker's Yeast
Sacchar. cerevisiae
P40016
523
60404
L257
A
S
D
F
I
S
K
L
E
Y
P
H
T
D
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.4
98.1
N.A.
97.1
97.1
N.A.
N.A.
88.3
82.7
82
N.A.
55.4
58.4
39.7
65.3
Protein Similarity:
100
N.A.
99.6
98.5
N.A.
97.7
97.7
N.A.
N.A.
92.3
87
88.3
N.A.
70.5
72.8
58.2
78.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
0
0
N.A.
0
0
6.6
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
20
26.6
N.A.
20
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.2
31.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.6
55.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
0
36
8
0
0
0
0
8
8
0
43
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
0
0
0
0
8
0
0
0
0
15
0
% D
% Glu:
0
43
29
8
0
0
0
0
8
8
8
43
0
0
0
% E
% Phe:
8
8
0
8
0
0
22
0
0
43
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
29
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
15
0
0
8
0
0
0
0
0
29
0
% I
% Lys:
0
0
43
8
0
0
50
0
0
0
0
0
0
0
29
% K
% Leu:
0
8
0
43
8
0
0
36
0
15
22
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
29
22
0
8
0
0
15
15
8
0
0
0
0
0
43
% N
% Pro:
0
8
8
0
0
0
0
0
0
0
50
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
43
0
0
% Q
% Arg:
0
0
0
0
0
36
0
0
0
0
0
8
36
0
0
% R
% Ser:
0
8
0
0
0
58
0
43
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
8
0
15
0
0
% T
% Val:
8
0
0
0
43
0
0
0
43
0
0
0
0
0
8
% V
% Trp:
0
0
0
29
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
0
29
36
0
8
8
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _