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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMD3 All Species: 27.27
Human Site: S352 Identified Species: 46.15
UniProt: O43242 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43242 NP_002800.2 534 60978 S352 R L Q F R Q P S L K R S L M P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094505 534 60977 S352 R L Q F R Q P S L K R S L M P
Dog Lupus familis XP_548138 534 60948 S352 R L Q F R Q P S L K R S L M P
Cat Felis silvestris
Mouse Mus musculus P14685 530 60681 S348 R L Q F R Q P S L K R S L M P
Rat Rattus norvegicus NP_001008282 530 60670 S348 R L Q F R Q P S L K R S L M P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026533 519 59378 S337 R L Q F R Q P S L K R S L M P
Frog Xenopus laevis NP_001085955 498 57453 L321 Q H C L K R S L M P Y F L L T
Zebra Danio Brachydanio rerio NP_956866 503 57904 S321 R L Q F R Q P S L K R S L M P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25161 494 55986 A320 G L R Q S L G A Y F Q L T Q A
Honey Bee Apis mellifera XP_623947 495 56922 L318 Q A A M R R A L A P Y F Q L T
Nematode Worm Caenorhab. elegans Q04908 504 57488 I320 R S V F R Q P I Y R K C L A H
Sea Urchin Strong. purpuratus XP_784007 501 57553 L325 Q S A Y K K T L V P Y F Q L T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LNU4 488 55564 V320 Y F E L T N A V R I G D L E L
Baker's Yeast Sacchar. cerevisiae P40016 523 60404 N337 L S F F H Q S N M Q K S L L P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.4 98.1 N.A. 97.1 97.1 N.A. N.A. 88.3 82.7 82 N.A. 55.4 58.4 39.7 65.3
Protein Similarity: 100 N.A. 99.6 98.5 N.A. 97.7 97.7 N.A. N.A. 92.3 87 88.3 N.A. 70.5 72.8 58.2 78.8
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 100 6.6 100 N.A. 6.6 6.6 40 0
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 100 40 100 N.A. 26.6 26.6 53.3 40
Percent
Protein Identity: N.A. N.A. N.A. 43.2 31.4 N.A.
Protein Similarity: N.A. N.A. N.A. 60.6 55.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 15 0 0 0 15 8 8 0 0 0 0 8 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % E
% Phe: 0 8 8 65 0 0 0 0 0 8 0 22 0 0 0 % F
% Gly: 8 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % G
% His: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % I
% Lys: 0 0 0 0 15 8 0 0 0 50 15 0 0 0 0 % K
% Leu: 8 58 0 15 0 8 0 22 50 0 0 8 79 29 8 % L
% Met: 0 0 0 8 0 0 0 0 15 0 0 0 0 50 0 % M
% Asn: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 58 0 0 22 0 0 0 0 58 % P
% Gln: 22 0 50 8 0 65 0 0 0 8 8 0 15 8 0 % Q
% Arg: 58 0 8 0 65 15 0 0 8 8 50 0 0 0 0 % R
% Ser: 0 22 0 0 8 0 15 50 0 0 0 58 0 0 0 % S
% Thr: 0 0 0 0 8 0 8 0 0 0 0 0 8 0 22 % T
% Val: 0 0 8 0 0 0 0 8 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 8 0 0 0 0 15 0 22 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _