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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMD3 All Species: 23.64
Human Site: T104 Identified Species: 40
UniProt: O43242 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43242 NP_002800.2 534 60978 T104 A L R M L P S T S R R L N H Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094505 534 60977 T104 A L R M L P S T S R R L N H Y
Dog Lupus familis XP_548138 534 60948 T104 A L R M L P S T S R R L N H Y
Cat Felis silvestris
Mouse Mus musculus P14685 530 60681 T100 A L R M L P S T S R R L N H Y
Rat Rattus norvegicus NP_001008282 530 60670 T100 A L R M L P S T S R R L N H Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026533 519 59378 T89 A L R A L P S T S R R L N A N
Frog Xenopus laevis NP_001085955 498 57453 G83 V V H K A I N G F F T S N P T
Zebra Danio Brachydanio rerio NP_956866 503 57904 V81 S R R L N T N V L H K A V S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25161 494 55986 A80 G V V F R N L A Q S I Y P A G
Honey Bee Apis mellifera XP_623947 495 56922 R80 R L N S N V L R G V I L S L Y
Nematode Worm Caenorhab. elegans Q04908 504 57488 L81 Y K L V S S H L S S D A Q F A
Sea Urchin Strong. purpuratus XP_784007 501 57553 G87 V L R K L I S G Y I P N G N T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LNU4 488 55564 S82 V P G S E A H S R L S S F V P
Baker's Yeast Sacchar. cerevisiae P40016 523 60404 S87 V L Y P D S S S F K K N L L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.4 98.1 N.A. 97.1 97.1 N.A. N.A. 88.3 82.7 82 N.A. 55.4 58.4 39.7 65.3
Protein Similarity: 100 N.A. 99.6 98.5 N.A. 97.7 97.7 N.A. N.A. 92.3 87 88.3 N.A. 70.5 72.8 58.2 78.8
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 80 6.6 6.6 N.A. 0 20 6.6 26.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 80 20 33.3 N.A. 6.6 26.6 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 43.2 31.4 N.A.
Protein Similarity: N.A. N.A. N.A. 60.6 55.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 43 0 0 8 8 8 0 8 0 0 0 15 0 15 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 15 8 0 0 8 8 0 % F
% Gly: 8 0 8 0 0 0 0 15 8 0 0 0 8 0 15 % G
% His: 0 0 8 0 0 0 15 0 0 8 0 0 0 36 0 % H
% Ile: 0 0 0 0 0 15 0 0 0 8 15 0 0 0 0 % I
% Lys: 0 8 0 15 0 0 0 0 0 8 15 0 0 0 8 % K
% Leu: 0 65 8 8 50 0 15 8 8 8 0 50 8 15 0 % L
% Met: 0 0 0 36 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 15 8 15 0 0 0 0 15 50 8 8 % N
% Pro: 0 8 0 8 0 43 0 0 0 0 8 0 8 8 8 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % Q
% Arg: 8 8 58 0 8 0 0 8 8 43 43 0 0 0 0 % R
% Ser: 8 0 0 15 8 15 58 15 50 15 8 15 8 8 0 % S
% Thr: 0 0 0 0 0 8 0 43 0 0 8 0 0 0 15 % T
% Val: 29 15 8 8 0 8 0 8 0 8 0 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 0 0 0 0 0 8 0 0 8 0 0 43 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _