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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMD3 All Species: 7.88
Human Site: T55 Identified Species: 13.33
UniProt: O43242 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43242 NP_002800.2 534 60978 T55 T G E A D G K T A A A A A E H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094505 534 60977 T55 T G E A D G K T A A A A A E H
Dog Lupus familis XP_548138 534 60948 A55 A G E P D S K A A A A A A E H
Cat Felis silvestris
Mouse Mus musculus P14685 530 60681 G51 G S T G E G D G K A A A T E H
Rat Rattus norvegicus NP_001008282 530 60670 G51 G S A G E G D G K A A A T E H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026533 519 59378 G40 E T A A V P A G E A G G E R Q
Frog Xenopus laevis NP_001085955 498 57453 T35 K K E L D S V T L E D I K E H
Zebra Danio Brachydanio rerio NP_956866 503 57904 R34 E E E Q R G A R E L D Q T T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25161 494 55986 A33 E K K N Q D V A A V Q E I R E
Honey Bee Apis mellifera XP_623947 495 56922 A33 D V C E K K D A D L Q T V Y D
Nematode Worm Caenorhab. elegans Q04908 504 57488 A33 E P A K D L N A I A V E N I K
Sea Urchin Strong. purpuratus XP_784007 501 57553 T39 K K E S D L I T L E D F K E H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LNU4 488 55564 I35 L K E I A A L I D T G S Y T K
Baker's Yeast Sacchar. cerevisiae P40016 523 60404 V37 Q V Q E L L K V L N E I S K T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.4 98.1 N.A. 97.1 97.1 N.A. N.A. 88.3 82.7 82 N.A. 55.4 58.4 39.7 65.3
Protein Similarity: 100 N.A. 99.6 98.5 N.A. 97.7 97.7 N.A. N.A. 92.3 87 88.3 N.A. 70.5 72.8 58.2 78.8
P-Site Identity: 100 N.A. 100 73.3 N.A. 40 40 N.A. N.A. 13.3 33.3 13.3 N.A. 6.6 0 13.3 33.3
P-Site Similarity: 100 N.A. 100 73.3 N.A. 46.6 46.6 N.A. N.A. 13.3 33.3 13.3 N.A. 13.3 0 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. 43.2 31.4 N.A.
Protein Similarity: N.A. N.A. N.A. 60.6 55.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 22 22 8 8 15 29 29 50 36 36 22 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 43 8 22 0 15 0 22 0 0 0 8 % D
% Glu: 29 8 50 15 15 0 0 0 15 15 8 15 8 50 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 15 22 0 15 0 36 0 22 0 0 15 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % H
% Ile: 0 0 0 8 0 0 8 8 8 0 0 15 8 8 0 % I
% Lys: 15 29 8 8 8 8 29 0 15 0 0 0 15 8 15 % K
% Leu: 8 0 0 8 8 22 8 0 22 15 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 8 0 0 8 0 0 8 0 0 % N
% Pro: 0 8 0 8 0 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 8 8 8 0 0 0 0 0 15 8 0 0 8 % Q
% Arg: 0 0 0 0 8 0 0 8 0 0 0 0 0 15 0 % R
% Ser: 0 15 0 8 0 15 0 0 0 0 0 8 8 0 0 % S
% Thr: 15 8 8 0 0 0 0 29 0 8 0 8 22 15 8 % T
% Val: 0 15 0 0 8 0 15 8 0 8 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _