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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPSS1
All Species:
30.61
Human Site:
Y574
Identified Species:
67.33
UniProt:
O43252
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43252
NP_005434.4
624
70833
Y574
K
K
K
K
R
M
D
Y
Y
D
S
E
H
H
E
Chimpanzee
Pan troglodytes
XP_517384
507
58054
F466
D
S
E
H
H
E
D
F
E
F
I
S
G
T
R
Rhesus Macaque
Macaca mulatta
XP_001085840
624
70873
Y574
K
K
K
K
R
M
D
Y
Y
D
S
E
H
H
E
Dog
Lupus familis
XP_851070
625
70990
Y575
K
K
K
K
R
M
D
Y
Y
D
S
E
H
H
E
Cat
Felis silvestris
Mouse
Mus musculus
Q60967
624
70776
Y574
K
K
K
K
R
M
D
Y
Y
D
S
E
H
H
E
Rat
Rattus norvegicus
NP_001099941
581
65884
Y531
K
K
K
K
R
M
D
Y
Y
D
S
D
H
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511666
625
70970
Y575
K
K
K
K
R
M
D
Y
Y
D
A
E
H
H
E
Chicken
Gallus gallus
XP_420493
800
89059
Y750
K
K
K
K
S
M
D
Y
Y
D
S
E
H
H
E
Frog
Xenopus laevis
NP_001090085
624
70455
Y574
K
K
K
K
C
M
D
Y
F
D
S
A
H
P
E
Zebra Danio
Brachydanio rerio
NP_001122171
624
70226
F574
K
V
K
K
A
M
D
F
Y
D
P
K
K
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177484
623
70280
F573
L
K
K
K
A
M
D
F
F
D
P
E
K
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.2
99.6
98.7
N.A.
98.7
90.8
N.A.
93.1
73.5
90.5
87.1
N.A.
N.A.
N.A.
N.A.
69
Protein Similarity:
100
81.2
99.8
99.3
N.A.
99.6
92.4
N.A.
96
76.2
95.5
94.2
N.A.
N.A.
N.A.
N.A.
81.5
P-Site Identity:
100
6.6
100
100
N.A.
100
93.3
N.A.
93.3
93.3
73.3
53.3
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
93.3
80
73.3
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
19
0
0
0
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
100
0
0
91
0
10
0
0
0
% D
% Glu:
0
0
10
0
0
10
0
0
10
0
0
64
0
0
82
% E
% Phe:
0
0
0
0
0
0
0
28
19
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
10
10
0
0
0
0
0
0
0
73
73
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
82
82
91
91
0
0
0
0
0
0
0
10
19
10
0
% K
% Leu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
91
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
19
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
55
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
10
0
0
10
0
0
0
0
0
64
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
73
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _