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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIAH2
All Species:
23.03
Human Site:
S121
Identified Species:
42.22
UniProt:
O43255
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43255
NP_005058.3
324
34615
S121
C
R
G
A
L
T
P
S
I
R
N
L
A
M
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_863586
282
31108
R83
R
G
P
L
G
S
I
R
N
L
A
M
E
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q06986
325
34739
S122
C
R
G
A
L
T
P
S
I
R
N
L
A
M
E
Rat
Rattus norvegicus
Q8R4T2
325
34681
S122
C
R
G
A
L
T
P
S
I
R
N
L
A
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507643
433
47638
S232
T
C
R
G
P
L
G
S
I
R
N
L
A
M
E
Chicken
Gallus gallus
XP_426719
319
34023
S116
C
R
G
S
L
T
P
S
I
R
N
L
A
M
E
Frog
Xenopus laevis
Q9I8X5
313
34081
N113
S
L
T
P
S
I
R
N
L
A
M
E
K
V
A
Zebra Danio
Brachydanio rerio
Q7SYL3
331
34475
S130
C
R
G
P
L
T
P
S
I
R
N
L
A
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21461
314
33689
N113
T
C
R
G
P
L
A
N
I
R
N
L
A
M
E
Honey Bee
Apis mellifera
XP_394284
279
30558
R80
R
G
P
L
G
N
I
R
N
L
A
M
E
K
V
Nematode Worm
Caenorhab. elegans
Q965X6
339
37641
S130
T
C
R
G
P
T
P
S
V
R
N
L
G
L
E
Sea Urchin
Strong. purpuratus
XP_797311
281
31248
R82
R
G
P
L
G
S
I
R
N
L
A
M
E
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9STN8
327
36556
E119
E
K
V
A
E
S
L
E
L
P
C
K
F
Y
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
70.6
N.A.
97.8
98.1
N.A.
56.5
91
85.8
76.1
N.A.
66.3
67.9
54.8
66.9
Protein Similarity:
100
N.A.
N.A.
78.4
N.A.
97.8
98.1
N.A.
63.9
93.5
88.2
82.4
N.A.
76.8
76.8
66.9
76.2
P-Site Identity:
100
N.A.
N.A.
0
N.A.
100
100
N.A.
53.3
93.3
0
93.3
N.A.
46.6
0
46.6
0
P-Site Similarity:
100
N.A.
N.A.
13.3
N.A.
100
100
N.A.
53.3
100
20
93.3
N.A.
53.3
6.6
60
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
31
0
0
8
0
0
8
24
0
54
0
8
% A
% Cys:
39
24
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
8
0
0
8
0
0
0
8
24
0
62
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
24
39
24
24
0
8
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
24
0
54
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
8
8
24
0
% K
% Leu:
0
8
0
24
39
16
8
0
16
24
0
62
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
24
0
54
0
% M
% Asn:
0
0
0
0
0
8
0
16
24
0
62
0
0
0
8
% N
% Pro:
0
0
24
16
24
0
47
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
24
39
24
0
0
0
8
24
0
62
0
0
0
0
0
% R
% Ser:
8
0
0
8
8
24
0
54
0
0
0
0
0
0
0
% S
% Thr:
24
0
8
0
0
47
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
8
0
0
0
0
8
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _