KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIAH2
All Species:
24.24
Human Site:
Y140
Identified Species:
44.44
UniProt:
O43255
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43255
NP_005058.3
324
34615
Y140
A
V
L
F
P
C
K
Y
A
T
T
G
C
S
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_863586
282
31108
S102
L
F
P
C
K
Y
A
S
S
G
C
E
I
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q06986
325
34739
Y141
A
V
L
F
P
C
K
Y
A
T
T
G
C
S
L
Rat
Rattus norvegicus
Q8R4T2
325
34681
Y141
A
V
L
F
P
C
K
Y
A
T
T
G
C
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507643
433
47638
Y251
S
V
L
F
P
C
K
Y
A
S
S
G
C
E
I
Chicken
Gallus gallus
XP_426719
319
34023
Y135
A
V
L
F
P
C
K
Y
A
T
T
G
C
S
L
Frog
Xenopus laevis
Q9I8X5
313
34081
T132
F
P
C
K
Y
A
S
T
G
C
S
L
S
L
H
Zebra Danio
Brachydanio rerio
Q7SYL3
331
34475
Y149
T
L
P
F
P
C
K
Y
S
S
A
G
C
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21461
314
33689
H132
N
V
K
F
P
C
K
H
S
G
Y
G
C
T
A
Honey Bee
Apis mellifera
XP_394284
279
30558
T99
M
F
P
C
K
Y
S
T
S
G
C
T
V
S
L
Nematode Worm
Caenorhab. elegans
Q965X6
339
37641
F149
T
V
R
F
P
C
K
F
S
T
S
G
C
P
L
Sea Urchin
Strong. purpuratus
XP_797311
281
31248
S101
M
F
P
C
R
Y
A
S
S
G
C
V
A
T
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9STN8
327
36556
K138
E
I
F
P
Y
Y
S
K
L
K
H
E
S
L
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
70.6
N.A.
97.8
98.1
N.A.
56.5
91
85.8
76.1
N.A.
66.3
67.9
54.8
66.9
Protein Similarity:
100
N.A.
N.A.
78.4
N.A.
97.8
98.1
N.A.
63.9
93.5
88.2
82.4
N.A.
76.8
76.8
66.9
76.2
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
100
100
N.A.
66.6
100
0
53.3
N.A.
46.6
13.3
60
0
P-Site Similarity:
100
N.A.
N.A.
20
N.A.
100
100
N.A.
93.3
100
6.6
73.3
N.A.
66.6
20
80
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
0
0
0
8
16
0
39
0
8
0
8
0
8
% A
% Cys:
0
0
8
24
0
62
0
0
0
8
24
0
62
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
16
0
8
0
% E
% Phe:
8
24
8
62
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
31
0
62
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
8
% I
% Lys:
0
0
8
8
16
0
62
8
0
8
0
0
0
0
0
% K
% Leu:
8
8
39
0
0
0
0
0
8
0
0
8
0
24
62
% L
% Met:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
31
8
62
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
24
16
47
16
24
0
16
39
0
% S
% Thr:
16
0
0
0
0
0
0
16
0
39
31
8
0
24
0
% T
% Val:
0
54
0
0
0
0
0
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
31
0
47
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _