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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNHIT1 All Species: 13.33
Human Site: S110 Identified Species: 26.67
UniProt: O43257 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43257 NP_006340.1 154 17536 S110 T A C A G P P S R P Q R P F C
Chimpanzee Pan troglodytes XP_001152206 72 8044 R29 A C A E S L S R P Q R S F Y A
Rhesus Macaque Macaca mulatta XP_001107895 168 19182 S124 T A C A G P P S R P Q R P F C
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8R331 154 17485 S110 T A C A G P P S R P Q R P F C
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521041 57 6077 C14 G P N Y V T A C A A P S S R P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001017401 154 17767 K110 T A C A E P S K I P Q R H F C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608895 151 17457 Q107 S A A A P A P Q K P L R H F C
Honey Bee Apis mellifera XP_391822 154 17746 K110 S A Q A P V S K F P E R Q F C
Nematode Worm Caenorhab. elegans NP_001122894 194 21997 E150 L S S A P P S E K P A R K F C
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002319400 172 19357 S128 A A V G P P S S T C R R H F C
Maize Zea mays NP_001132577 100 11177 S57 A V G P P S T S S R R H Y C S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03433 280 32003 S153 S A L M G G S S F V K E H S K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.6 89.8 N.A. N.A. 97.4 N.A. N.A. 33.1 N.A. N.A. 79.8 N.A. 54.5 54.5 38.1 N.A.
Protein Similarity: 100 40.2 90.4 N.A. N.A. 98.6 N.A. N.A. 34.4 N.A. N.A. 87 N.A. 70.7 73.3 52.5 N.A.
P-Site Identity: 100 0 100 N.A. N.A. 100 N.A. N.A. 0 N.A. N.A. 66.6 N.A. 46.6 40 40 N.A.
P-Site Similarity: 100 13.3 100 N.A. N.A. 100 N.A. N.A. 0 N.A. N.A. 66.6 N.A. 60 53.3 53.3 N.A.
Percent
Protein Identity: 34.3 25.9 N.A. N.A. 23.2 N.A.
Protein Similarity: 46.5 40.2 N.A. N.A. 35.3 N.A.
P-Site Identity: 40 6.6 N.A. N.A. 20 N.A.
P-Site Similarity: 46.6 13.3 N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 67 17 59 0 9 9 0 9 9 9 0 0 0 9 % A
% Cys: 0 9 34 0 0 0 0 9 0 9 0 0 0 9 67 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 9 9 0 0 9 0 0 9 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 17 0 0 0 9 67 0 % F
% Gly: 9 0 9 9 34 9 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 34 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 17 17 0 9 0 9 0 9 % K
% Leu: 9 0 9 0 0 9 0 0 0 0 9 0 0 0 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 9 0 9 42 50 34 0 9 59 9 0 25 0 9 % P
% Gln: 0 0 9 0 0 0 0 9 0 9 34 0 9 0 0 % Q
% Arg: 0 0 0 0 0 0 0 9 25 9 25 67 0 9 0 % R
% Ser: 25 9 9 0 9 9 50 50 9 0 0 17 9 9 9 % S
% Thr: 34 0 0 0 0 9 9 0 9 0 0 0 0 0 0 % T
% Val: 0 9 9 0 9 9 0 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _