KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZW10
All Species:
16.97
Human Site:
S243
Identified Species:
28.72
UniProt:
O43264
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43264
NP_004715.1
779
88829
S243
E
L
H
S
K
L
K
S
F
G
Q
M
L
L
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085694
778
88561
S243
E
L
H
S
K
L
K
S
F
G
Q
M
L
L
K
Dog
Lupus familis
XP_536569
779
88803
S243
E
L
Q
M
K
L
K
S
F
G
Q
L
L
L
K
Cat
Felis silvestris
Mouse
Mus musculus
O54692
779
88044
S243
E
L
P
T
K
L
K
S
F
G
Q
M
L
L
K
Rat
Rattus norvegicus
Q4V8C2
777
87948
S242
E
L
P
T
K
L
K
S
F
G
Q
M
L
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507667
639
71489
P149
S
D
L
E
R
P
S
P
P
E
V
F
S
K
I
Chicken
Gallus gallus
NP_989914
753
85635
F240
S
Y
P
F
L
Q
P
F
V
E
E
Q
S
D
V
Frog
Xenopus laevis
NP_001131044
776
88019
F242
E
L
N
T
K
L
K
F
F
S
Q
L
L
L
N
Zebra Danio
Brachydanio rerio
NP_956435
771
87302
K241
I
Q
G
E
L
H
K
K
I
K
L
F
G
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4X9
721
82245
Q231
S
R
D
Q
T
Q
L
Q
D
I
V
Q
A
L
F
Honey Bee
Apis mellifera
XP_001121600
710
82808
N220
Q
S
L
H
H
I
D
N
L
S
N
Y
L
H
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789289
745
83639
H241
F
S
K
K
L
L
E
H
V
L
H
P
I
I
R
Poplar Tree
Populus trichocarpa
XP_002301597
767
86905
K241
I
L
D
Y
G
F
A
K
V
A
D
Q
M
I
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48626
742
83915
K243
I
L
D
Y
G
L
A
K
A
A
D
S
I
F
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
91.5
N.A.
86.1
85.3
N.A.
60.7
68.1
70.4
60.2
N.A.
23.3
31.7
N.A.
39.2
Protein Similarity:
100
N.A.
99.3
95.1
N.A.
92.5
92
N.A.
71.2
82.6
84.8
77.6
N.A.
41
52.2
N.A.
59.3
P-Site Identity:
100
N.A.
100
80
N.A.
86.6
86.6
N.A.
0
0
60
6.6
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
N.A.
100
86.6
N.A.
93.3
93.3
N.A.
6.6
6.6
80
6.6
N.A.
6.6
33.3
N.A.
33.3
Percent
Protein Identity:
22.2
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
45.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
15
0
8
15
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
22
0
0
0
8
0
8
0
15
0
0
8
0
% D
% Glu:
43
0
0
15
0
0
8
0
0
15
8
0
0
0
0
% E
% Phe:
8
0
0
8
0
8
0
15
43
0
0
15
0
8
8
% F
% Gly:
0
0
8
0
15
0
0
0
0
36
0
0
8
0
0
% G
% His:
0
0
15
8
8
8
0
8
0
0
8
0
0
8
0
% H
% Ile:
22
0
0
0
0
8
0
0
8
8
0
0
15
15
8
% I
% Lys:
0
0
8
8
43
0
50
22
0
8
0
0
0
8
58
% K
% Leu:
0
58
15
0
22
58
8
0
8
8
8
15
50
50
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
29
8
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
0
0
8
0
0
0
8
% N
% Pro:
0
0
22
0
0
8
8
8
8
0
0
8
0
0
0
% P
% Gln:
8
8
8
8
0
15
0
8
0
0
43
22
0
8
0
% Q
% Arg:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
22
15
0
15
0
0
8
36
0
15
0
8
15
0
0
% S
% Thr:
0
0
0
22
8
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
22
0
15
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
15
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _