Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZW10 All Species: 31.82
Human Site: S350 Identified Species: 53.85
UniProt: O43264 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43264 NP_004715.1 779 88829 S350 I K N C L V Y S I P T N S S K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001085694 778 88561 S349 I K N C L V Y S I P T N S S K
Dog Lupus familis XP_536569 779 88803 S350 I K N C L V Y S I P T N S S K
Cat Felis silvestris
Mouse Mus musculus O54692 779 88044 S350 I R N C L V Y S I P T N S S K
Rat Rattus norvegicus Q4V8C2 777 87948 S349 I R N C L V Y S I P T N S S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507667 639 71489 K250 G D A T D L L K Y A R N V N S
Chicken Gallus gallus NP_989914 753 85635 S342 Q Y I E V I K S T E E F E K A
Frog Xenopus laevis NP_001131044 776 88019 S349 I K D C L V Y S I P N N S S K
Zebra Danio Brachydanio rerio NP_956435 771 87302 S343 I R E C L V H S I P A N S S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W4X9 721 82245 H332 V F G I I G D H V K D K M L K
Honey Bee Apis mellifera XP_001121600 710 82808 T321 N D C I S R I T P T S S A D L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789289 745 83639 S342 I K D C L T P S I P V T S T E
Poplar Tree Populus trichocarpa XP_002301597 767 86905 A342 I S N F L S K A V P E D A S K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O48626 742 83915 V345 I S K F L S K V V P E D A S K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.5 91.5 N.A. 86.1 85.3 N.A. 60.7 68.1 70.4 60.2 N.A. 23.3 31.7 N.A. 39.2
Protein Similarity: 100 N.A. 99.3 95.1 N.A. 92.5 92 N.A. 71.2 82.6 84.8 77.6 N.A. 41 52.2 N.A. 59.3
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 6.6 6.6 86.6 66.6 N.A. 6.6 0 N.A. 53.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 20 20 93.3 86.6 N.A. 26.6 26.6 N.A. 73.3
Percent
Protein Identity: 22.2 N.A. N.A. 21.6 N.A. N.A.
Protein Similarity: 45.1 N.A. N.A. 42.7 N.A. N.A.
P-Site Identity: 40 N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: 66.6 N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 8 0 8 8 0 22 0 8 % A
% Cys: 0 0 8 58 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 15 0 8 0 8 0 0 0 8 15 0 8 0 % D
% Glu: 0 0 8 8 0 0 0 0 0 8 22 0 8 0 8 % E
% Phe: 0 8 0 15 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 8 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % H
% Ile: 72 0 8 15 8 8 8 0 58 0 0 0 0 0 0 % I
% Lys: 0 36 8 0 0 0 22 8 0 8 0 8 0 8 65 % K
% Leu: 0 0 0 0 72 8 8 0 0 0 0 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 0 43 0 0 0 0 0 0 0 8 58 0 8 0 % N
% Pro: 0 0 0 0 0 0 8 0 8 72 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 22 0 0 0 8 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 15 0 0 8 15 0 65 0 0 8 8 58 65 8 % S
% Thr: 0 0 0 8 0 8 0 8 8 8 36 8 0 8 0 % T
% Val: 8 0 0 0 8 50 0 8 22 0 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 43 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _