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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZW10
All Species:
26.67
Human Site:
S75
Identified Species:
45.13
UniProt:
O43264
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43264
NP_004715.1
779
88829
S75
E
D
I
D
L
L
K
S
R
I
E
S
E
V
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085694
778
88561
S75
E
D
I
D
L
L
K
S
R
I
E
S
E
V
C
Dog
Lupus familis
XP_536569
779
88803
S75
E
D
I
D
L
L
K
S
R
I
E
S
E
V
R
Cat
Felis silvestris
Mouse
Mus musculus
O54692
779
88044
S75
N
D
I
D
Q
L
K
S
R
I
E
T
E
V
C
Rat
Rattus norvegicus
Q4V8C2
777
87948
S75
N
D
I
D
Q
L
K
S
R
I
E
T
E
V
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507667
639
71489
Chicken
Gallus gallus
NP_989914
753
85635
L75
F
T
E
L
K
Q
Q
L
E
Q
D
T
L
V
L
Frog
Xenopus laevis
NP_001131044
776
88019
S75
S
D
V
D
V
L
K
S
R
I
E
T
E
V
K
Zebra Danio
Brachydanio rerio
NP_956435
771
87302
S75
K
D
I
D
L
L
K
S
C
I
E
N
E
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4X9
721
82245
F67
N
N
T
S
P
D
I
F
L
E
E
S
G
S
L
Honey Bee
Apis mellifera
XP_001121600
710
82808
D56
F
T
S
K
L
T
R
D
Q
H
L
V
L
K
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789289
745
83639
D75
T
E
M
Q
D
L
G
D
K
I
Q
G
D
I
R
Poplar Tree
Populus trichocarpa
XP_002301597
767
86905
D75
N
D
A
V
S
R
T
D
Q
I
N
Q
C
L
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48626
742
83915
T77
C
Q
D
T
V
S
R
T
R
L
I
S
D
D
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
91.5
N.A.
86.1
85.3
N.A.
60.7
68.1
70.4
60.2
N.A.
23.3
31.7
N.A.
39.2
Protein Similarity:
100
N.A.
99.3
95.1
N.A.
92.5
92
N.A.
71.2
82.6
84.8
77.6
N.A.
41
52.2
N.A.
59.3
P-Site Identity:
100
N.A.
93.3
100
N.A.
73.3
73.3
N.A.
0
6.6
66.6
73.3
N.A.
13.3
6.6
N.A.
20
P-Site Similarity:
100
N.A.
93.3
100
N.A.
80
80
N.A.
0
26.6
93.3
93.3
N.A.
20
20
N.A.
60
Percent
Protein Identity:
22.2
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
45.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
8
0
0
0
8
0
22
% C
% Asp:
0
58
8
50
8
8
0
22
0
0
8
0
15
8
0
% D
% Glu:
22
8
8
0
0
0
0
0
8
8
58
0
50
0
0
% E
% Phe:
15
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
8
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
43
0
0
0
8
0
0
65
8
0
0
8
0
% I
% Lys:
8
0
0
8
8
0
50
0
8
0
0
0
0
8
8
% K
% Leu:
0
0
0
8
36
58
0
8
8
8
8
0
15
8
22
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
29
8
0
0
0
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
15
8
8
0
15
8
8
8
0
0
8
% Q
% Arg:
0
0
0
0
0
8
15
0
50
0
0
0
0
0
22
% R
% Ser:
8
0
8
8
8
8
0
50
0
0
0
36
0
8
0
% S
% Thr:
8
15
8
8
0
8
8
8
0
0
0
29
0
0
0
% T
% Val:
0
0
8
8
15
0
0
0
0
0
0
8
0
58
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _