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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZW10
All Species:
28.18
Human Site:
Y716
Identified Species:
47.69
UniProt:
O43264
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43264
NP_004715.1
779
88829
Y716
Y
Q
E
E
V
P
V
Y
V
P
K
W
M
P
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085694
778
88561
Y715
Y
Q
E
E
V
P
V
Y
V
P
K
W
M
P
F
Dog
Lupus familis
XP_536569
779
88803
Y716
Y
Q
E
E
V
P
V
Y
V
S
K
W
M
P
F
Cat
Felis silvestris
Mouse
Mus musculus
O54692
779
88044
Y716
Y
Q
E
E
V
P
V
Y
V
S
K
W
M
P
F
Rat
Rattus norvegicus
Q4V8C2
777
87948
Y714
Y
Q
E
E
V
P
V
Y
V
S
K
W
M
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507667
639
71489
M587
W
M
A
F
G
E
L
M
V
M
L
Q
A
S
L
Chicken
Gallus gallus
NP_989914
753
85635
Y690
Y
Q
E
E
V
P
V
Y
V
Q
K
W
T
T
F
Frog
Xenopus laevis
NP_001131044
776
88019
Y713
Y
Q
E
E
V
T
L
Y
V
Q
K
W
M
K
F
Zebra Danio
Brachydanio rerio
NP_956435
771
87302
Y707
Y
Q
E
E
V
P
V
Y
V
K
K
W
M
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4X9
721
82245
K669
W
L
K
L
Q
Q
L
K
A
M
L
N
A
S
L
Honey Bee
Apis mellifera
XP_001121600
710
82808
I658
W
E
K
F
L
E
L
I
Q
I
L
G
A
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789289
745
83639
R684
E
V
M
V
K
E
W
R
Q
F
L
E
L
G
F
Poplar Tree
Populus trichocarpa
XP_002301597
767
86905
L689
P
E
E
Y
H
T
S
L
V
D
D
L
I
P
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48626
742
83915
L689
K
T
R
K
L
A
E
L
L
D
M
P
L
M
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
91.5
N.A.
86.1
85.3
N.A.
60.7
68.1
70.4
60.2
N.A.
23.3
31.7
N.A.
39.2
Protein Similarity:
100
N.A.
99.3
95.1
N.A.
92.5
92
N.A.
71.2
82.6
84.8
77.6
N.A.
41
52.2
N.A.
59.3
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
6.6
80
73.3
80
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
20
80
80
80
N.A.
20
33.3
N.A.
13.3
Percent
Protein Identity:
22.2
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
45.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
0
8
0
0
0
22
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
15
8
0
0
0
0
% D
% Glu:
8
15
65
58
0
22
8
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
15
0
0
0
0
0
8
0
0
0
0
58
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
8
0
8
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
8
0
0
8
0
0
% I
% Lys:
8
0
15
8
8
0
0
8
0
8
58
0
0
8
0
% K
% Leu:
0
8
0
8
15
0
29
15
8
0
29
8
15
0
29
% L
% Met:
0
8
8
0
0
0
0
8
0
15
8
0
50
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
8
0
0
0
0
50
0
0
0
15
0
8
0
43
0
% P
% Gln:
0
58
0
0
8
8
0
0
15
15
0
8
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
0
0
22
0
0
0
22
15
% S
% Thr:
0
8
0
0
0
15
0
0
0
0
0
0
8
15
0
% T
% Val:
0
8
0
8
58
0
50
0
72
0
0
0
0
0
0
% V
% Trp:
22
0
0
0
0
0
8
0
0
0
0
58
0
0
0
% W
% Tyr:
58
0
0
8
0
0
0
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _