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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRODH
All Species:
7.88
Human Site:
S485
Identified Species:
13.33
UniProt:
O43272
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43272
NP_057419.3
516
59231
S485
S
R
R
A
L
E
N
S
S
L
M
K
G
T
H
Chimpanzee
Pan troglodytes
XP_525525
354
39491
V326
Y
H
R
C
L
D
Y
V
L
E
E
L
K
H
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534757
639
71930
S608
S
R
R
A
L
E
N
S
S
V
M
K
G
A
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU79
497
56755
S466
S
R
R
A
L
E
N
S
S
I
M
K
G
A
Q
Rat
Rattus norvegicus
Q2V057
456
50984
E428
Y
L
I
R
R
A
Q
E
N
R
S
V
L
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234062
527
59659
A494
R
K
A
N
V
M
V
A
T
H
N
E
D
T
V
Frog
Xenopus laevis
Q6PAY6
466
52311
Q438
P
Y
L
I
R
R
A
Q
E
N
Q
S
V
L
Q
Zebra Danio
Brachydanio rerio
XP_002665916
617
71033
R585
S
R
R
A
Q
E
N
R
G
F
M
K
G
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04499
681
77135
K644
S
R
R
A
Q
E
N
K
G
V
L
K
K
I
K
Honey Bee
Apis mellifera
XP_395275
528
60938
R491
S
R
R
A
Q
E
N
R
G
I
L
K
K
I
K
Nematode Worm
Caenorhab. elegans
O45228
616
69804
G582
S
R
R
A
L
E
N
G
S
V
L
K
K
A
N
Sea Urchin
Strong. purpuratus
XP_788908
295
34364
M267
R
A
Q
E
N
S
G
M
L
K
G
V
T
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92983
499
54937
A469
I
P
Y
L
L
R
R
A
Y
E
N
R
G
M
M
Baker's Yeast
Sacchar. cerevisiae
P09368
476
53253
Q448
D
Y
L
L
R
R
L
Q
E
N
G
D
A
V
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.9
N.A.
71.5
N.A.
81.9
32.5
N.A.
N.A.
58
31.3
59.3
N.A.
39.6
47.7
40.9
37.9
Protein Similarity:
100
56
N.A.
76.8
N.A.
88.5
46.1
N.A.
N.A.
69
48.4
70
N.A.
53.4
65.3
56.6
46.9
P-Site Identity:
100
13.3
N.A.
80
N.A.
80
0
N.A.
N.A.
6.6
0
60
N.A.
46.6
46.6
60
0
P-Site Similarity:
100
26.6
N.A.
86.6
N.A.
86.6
6.6
N.A.
N.A.
40
0
66.6
N.A.
60
60
80
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
38.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
50
0
8
8
15
0
0
0
0
8
22
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
0
0
0
0
8
8
0
0
% D
% Glu:
0
0
0
8
0
50
0
8
15
15
8
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
8
22
0
15
0
36
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
8
0
0
0
8
8
% H
% Ile:
8
0
8
8
0
0
0
0
0
15
0
0
0
15
0
% I
% Lys:
0
8
0
0
0
0
0
8
0
8
0
50
29
0
15
% K
% Leu:
0
8
15
15
43
0
8
0
15
8
22
8
8
8
0
% L
% Met:
0
0
0
0
0
8
0
8
0
0
29
0
0
8
8
% M
% Asn:
0
0
0
8
8
0
50
0
8
15
15
0
0
0
15
% N
% Pro:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
22
0
8
15
0
0
8
0
0
15
22
% Q
% Arg:
15
50
58
8
22
22
8
15
0
8
0
8
0
0
8
% R
% Ser:
50
0
0
0
0
8
0
22
29
0
8
8
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
8
15
0
% T
% Val:
0
0
0
0
8
0
8
8
0
22
0
15
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
15
15
8
0
0
0
8
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _