KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRODH
All Species:
12.12
Human Site:
S81
Identified Species:
20.51
UniProt:
O43272
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43272
NP_057419.3
516
59231
S81
K
E
M
E
S
C
T
S
A
A
E
R
D
G
S
Chimpanzee
Pan troglodytes
XP_525525
354
39491
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534757
639
71930
S204
K
E
M
E
S
C
T
S
A
V
E
R
E
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU79
497
56755
K76
S
G
A
N
K
R
E
K
Q
Y
Q
V
H
P
A
Rat
Rattus norvegicus
Q2V057
456
50984
V53
L
C
A
W
P
P
L
V
T
H
G
L
A
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234062
527
59659
E77
R
L
R
A
F
N
T
E
S
R
P
S
P
Q
A
Frog
Xenopus laevis
Q6PAY6
466
52311
L63
W
E
V
A
R
G
L
L
I
F
R
M
C
S
F
Zebra Danio
Brachydanio rerio
XP_002665916
617
71033
S181
K
E
M
D
S
C
V
S
E
A
E
K
E
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04499
681
77135
S228
R
E
V
E
S
S
V
S
S
A
G
D
K
K
E
Honey Bee
Apis mellifera
XP_395275
528
60938
S85
R
E
M
Q
G
S
V
S
E
A
G
D
E
K
R
Nematode Worm
Caenorhab. elegans
O45228
616
69804
V171
K
T
V
K
G
T
S
V
A
T
V
K
P
A
A
Sea Urchin
Strong. purpuratus
XP_788908
295
34364
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92983
499
54937
D79
F
S
S
I
P
T
S
D
L
L
R
S
T
A
V
Baker's Yeast
Sacchar. cerevisiae
P09368
476
53253
L73
Q
T
L
P
K
K
E
L
F
Q
L
G
F
I
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.9
N.A.
71.5
N.A.
81.9
32.5
N.A.
N.A.
58
31.3
59.3
N.A.
39.6
47.7
40.9
37.9
Protein Similarity:
100
56
N.A.
76.8
N.A.
88.5
46.1
N.A.
N.A.
69
48.4
70
N.A.
53.4
65.3
56.6
46.9
P-Site Identity:
100
0
N.A.
86.6
N.A.
0
0
N.A.
N.A.
6.6
6.6
53.3
N.A.
33.3
26.6
13.3
0
P-Site Similarity:
100
0
N.A.
93.3
N.A.
13.3
0
N.A.
N.A.
26.6
13.3
73.3
N.A.
53.3
46.6
46.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
38.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
15
0
0
0
0
22
29
0
0
8
15
22
% A
% Cys:
0
8
0
0
0
22
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
8
0
0
0
8
0
0
0
15
8
0
0
% D
% Glu:
0
43
0
22
0
0
15
8
15
0
22
0
22
0
8
% E
% Phe:
8
0
0
0
8
0
0
0
8
8
0
0
8
8
8
% F
% Gly:
0
8
0
0
15
8
0
0
0
0
22
8
0
15
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
8
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
0
0
0
8
0
% I
% Lys:
29
0
0
8
15
8
0
8
0
0
0
15
8
15
0
% K
% Leu:
8
8
8
0
0
0
15
15
8
8
8
8
0
0
0
% L
% Met:
0
0
29
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
15
8
0
0
0
0
8
0
15
8
0
% P
% Gln:
8
0
0
8
0
0
0
0
8
8
8
0
0
8
8
% Q
% Arg:
22
0
8
0
8
8
0
0
0
8
15
15
0
0
8
% R
% Ser:
8
8
8
0
29
15
15
36
15
0
0
15
0
15
15
% S
% Thr:
0
15
0
0
0
15
22
0
8
8
0
0
8
0
0
% T
% Val:
0
0
22
0
0
0
22
15
0
8
8
8
0
0
8
% V
% Trp:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _