Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRODH All Species: 30
Human Site: Y362 Identified Species: 50.77
UniProt: O43272 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43272 NP_057419.3 516 59231 Y362 A K L V R G A Y L A Q E R A R
Chimpanzee Pan troglodytes XP_525525 354 39491 L211 M L Q W M D V L A K K A T E M
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534757 639 71930 Y485 A K L V R G A Y M A Q E R T R
Cat Felis silvestris
Mouse Mus musculus Q9WU79 497 56755 Y343 A K L V R R A Y M A Q E R V R
Rat Rattus norvegicus Q2V057 456 50984 S313 A Y L D K E R S V T Q L H G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234062 527 59659 R356 E E E L Q M K R M L Q R M D V
Frog Xenopus laevis Q6PAY6 466 52311 K323 A Y M D K E R K L S K Q K G Y
Zebra Danio Brachydanio rerio XP_002665916 617 71033 Y462 A K L V R G A Y M C Q E R S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q04499 681 77135 Y514 A K L V R G A Y M D Q E R D R
Honey Bee Apis mellifera XP_395275 528 60938 Y361 A K L V R G A Y I E Q E R A R
Nematode Worm Caenorhab. elegans O45228 616 69804 Y457 A K L V R G A Y M E Q E R A R
Sea Urchin Strong. purpuratus XP_788908 295 34364 D152 Q E R Q R A E D I G Y D D P I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92983 499 54937 Y350 F K L V R G A Y M S S E A S L
Baker's Yeast Sacchar. cerevisiae P09368 476 53253 N333 A Y I H S E K N R N Q I I F G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.9 N.A. 71.5 N.A. 81.9 32.5 N.A. N.A. 58 31.3 59.3 N.A. 39.6 47.7 40.9 37.9
Protein Similarity: 100 56 N.A. 76.8 N.A. 88.5 46.1 N.A. N.A. 69 48.4 70 N.A. 53.4 65.3 56.6 46.9
P-Site Identity: 100 0 N.A. 86.6 N.A. 80 20 N.A. N.A. 6.6 13.3 80 N.A. 80 86.6 86.6 6.6
P-Site Similarity: 100 6.6 N.A. 93.3 N.A. 86.6 40 N.A. N.A. 33.3 53.3 93.3 N.A. 86.6 93.3 93.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 25.9 21.1 N.A.
Protein Similarity: N.A. N.A. N.A. 44.5 38.9 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 72 0 0 0 0 8 58 0 8 22 0 8 8 22 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 15 0 8 0 8 0 8 0 8 8 15 0 % D
% Glu: 8 15 8 0 0 22 8 0 0 15 0 58 0 8 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 50 0 0 0 8 0 0 0 15 8 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 15 0 0 8 8 0 8 % I
% Lys: 0 58 0 0 15 0 15 8 0 8 15 0 8 0 8 % K
% Leu: 0 8 65 8 0 0 0 8 15 8 0 8 0 0 8 % L
% Met: 8 0 8 0 8 8 0 0 50 0 0 0 8 0 8 % M
% Asn: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 8 0 8 8 8 0 0 0 0 0 72 8 0 0 0 % Q
% Arg: 0 0 8 0 65 8 15 8 8 0 0 8 50 0 50 % R
% Ser: 0 0 0 0 8 0 0 8 0 15 8 0 0 15 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 8 0 0 8 8 0 % T
% Val: 0 0 0 58 0 0 8 0 8 0 0 0 0 8 8 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 22 0 0 0 0 0 58 0 0 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _