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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRODH
All Species:
30
Human Site:
Y362
Identified Species:
50.77
UniProt:
O43272
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43272
NP_057419.3
516
59231
Y362
A
K
L
V
R
G
A
Y
L
A
Q
E
R
A
R
Chimpanzee
Pan troglodytes
XP_525525
354
39491
L211
M
L
Q
W
M
D
V
L
A
K
K
A
T
E
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534757
639
71930
Y485
A
K
L
V
R
G
A
Y
M
A
Q
E
R
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU79
497
56755
Y343
A
K
L
V
R
R
A
Y
M
A
Q
E
R
V
R
Rat
Rattus norvegicus
Q2V057
456
50984
S313
A
Y
L
D
K
E
R
S
V
T
Q
L
H
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234062
527
59659
R356
E
E
E
L
Q
M
K
R
M
L
Q
R
M
D
V
Frog
Xenopus laevis
Q6PAY6
466
52311
K323
A
Y
M
D
K
E
R
K
L
S
K
Q
K
G
Y
Zebra Danio
Brachydanio rerio
XP_002665916
617
71033
Y462
A
K
L
V
R
G
A
Y
M
C
Q
E
R
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04499
681
77135
Y514
A
K
L
V
R
G
A
Y
M
D
Q
E
R
D
R
Honey Bee
Apis mellifera
XP_395275
528
60938
Y361
A
K
L
V
R
G
A
Y
I
E
Q
E
R
A
R
Nematode Worm
Caenorhab. elegans
O45228
616
69804
Y457
A
K
L
V
R
G
A
Y
M
E
Q
E
R
A
R
Sea Urchin
Strong. purpuratus
XP_788908
295
34364
D152
Q
E
R
Q
R
A
E
D
I
G
Y
D
D
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92983
499
54937
Y350
F
K
L
V
R
G
A
Y
M
S
S
E
A
S
L
Baker's Yeast
Sacchar. cerevisiae
P09368
476
53253
N333
A
Y
I
H
S
E
K
N
R
N
Q
I
I
F
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.9
N.A.
71.5
N.A.
81.9
32.5
N.A.
N.A.
58
31.3
59.3
N.A.
39.6
47.7
40.9
37.9
Protein Similarity:
100
56
N.A.
76.8
N.A.
88.5
46.1
N.A.
N.A.
69
48.4
70
N.A.
53.4
65.3
56.6
46.9
P-Site Identity:
100
0
N.A.
86.6
N.A.
80
20
N.A.
N.A.
6.6
13.3
80
N.A.
80
86.6
86.6
6.6
P-Site Similarity:
100
6.6
N.A.
93.3
N.A.
86.6
40
N.A.
N.A.
33.3
53.3
93.3
N.A.
86.6
93.3
93.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
38.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
72
0
0
0
0
8
58
0
8
22
0
8
8
22
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
15
0
8
0
8
0
8
0
8
8
15
0
% D
% Glu:
8
15
8
0
0
22
8
0
0
15
0
58
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
50
0
0
0
8
0
0
0
15
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
15
0
0
8
8
0
8
% I
% Lys:
0
58
0
0
15
0
15
8
0
8
15
0
8
0
8
% K
% Leu:
0
8
65
8
0
0
0
8
15
8
0
8
0
0
8
% L
% Met:
8
0
8
0
8
8
0
0
50
0
0
0
8
0
8
% M
% Asn:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
8
0
8
8
8
0
0
0
0
0
72
8
0
0
0
% Q
% Arg:
0
0
8
0
65
8
15
8
8
0
0
8
50
0
50
% R
% Ser:
0
0
0
0
8
0
0
8
0
15
8
0
0
15
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
8
8
0
% T
% Val:
0
0
0
58
0
0
8
0
8
0
0
0
0
8
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
22
0
0
0
0
0
58
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _