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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPINT1
All Species:
24.55
Human Site:
Y522
Identified Species:
67.5
UniProt:
O43278
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43278
NP_001027539.1
529
58398
Y522
E
D
T
E
H
L
V
Y
N
H
T
T
R
P
L
Chimpanzee
Pan troglodytes
XP_510316
666
73074
Y659
E
D
T
E
H
L
V
Y
N
H
T
T
R
P
L
Rhesus Macaque
Macaca mulatta
Q28864
304
35067
Dog
Lupus familis
XP_544625
561
62347
Y554
E
D
T
E
H
L
V
Y
N
H
T
T
R
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9R097
507
56659
Y500
E
D
T
E
H
L
V
Y
N
H
T
T
Q
P
L
Rat
Rattus norvegicus
Q02445
302
34535
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518665
481
53346
Y474
E
D
T
E
H
L
V
Y
N
H
T
T
K
P
L
Chicken
Gallus gallus
XP_421130
467
52878
Y460
E
D
T
E
H
L
F
Y
N
G
A
T
K
P
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001104693
499
55338
Y492
E
D
D
Q
Q
M
V
Y
S
S
T
T
A
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
23.6
74.5
N.A.
77.5
20.4
N.A.
54.8
47.2
N.A.
38.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
74
34.9
79.5
N.A.
85
34.4
N.A.
67.6
61
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
93.3
0
N.A.
93.3
66.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
100
N.A.
100
0
N.A.
100
80
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
78
12
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
78
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
0
67
0
0
0
0
56
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
23
12
0
% K
% Leu:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
56
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% P
% Gln:
0
0
0
12
12
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
34
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% S
% Thr:
0
0
67
0
0
0
0
0
0
0
67
78
0
0
0
% T
% Val:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
78
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _