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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TREH
All Species:
30.3
Human Site:
S222
Identified Species:
74.07
UniProt:
O43280
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43280
NP_009111.2
583
66568
S222
R
V
Y
Y
L
Q
R
S
Q
P
P
L
L
T
L
Chimpanzee
Pan troglodytes
XP_522200
583
66612
S222
R
V
Y
Y
L
Q
R
S
Q
P
P
L
L
T
L
Rhesus Macaque
Macaca mulatta
XP_001094826
486
55076
T162
A
L
E
L
D
F
W
T
K
N
R
T
V
S
V
Dog
Lupus familis
XP_546498
751
84039
S348
R
V
Y
Y
L
Q
R
S
Q
P
P
L
L
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLT2
576
65383
S219
R
I
Y
Y
L
Q
R
S
Q
P
P
L
L
T
L
Rat
Rattus norvegicus
NP_001129613
576
65603
S219
R
V
Y
Y
L
Q
R
S
H
P
P
L
L
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001336187
577
65839
S218
R
V
Y
Y
E
R
R
S
Q
P
P
F
L
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2M2
596
67670
S247
R
V
Y
Y
H
G
R
S
Q
P
P
L
L
T
G
Honey Bee
Apis mellifera
A8J4S9
626
72798
S235
R
I
Y
Y
T
M
R
S
Q
P
P
M
L
I
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195993
539
61740
I208
T
F
L
P
D
L
E
I
E
Y
Q
F
W
M
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
80
61.5
N.A.
81.4
81.4
N.A.
N.A.
N.A.
N.A.
52.1
N.A.
42.1
42.4
N.A.
41.5
Protein Similarity:
100
99.1
81.4
68.1
N.A.
88.8
89
N.A.
N.A.
N.A.
N.A.
68.6
N.A.
60.9
61
N.A.
57.1
P-Site Identity:
100
100
0
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
80
60
N.A.
0
P-Site Similarity:
100
100
40
100
N.A.
100
93.3
N.A.
N.A.
N.A.
N.A.
80
N.A.
80
73.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
10
0
10
0
10
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
10
0
0
0
0
0
20
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
20
0
0
0
0
0
10
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
10
10
10
50
10
0
0
0
0
0
60
80
0
60
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
10
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
80
80
0
0
10
10
% P
% Gln:
0
0
0
0
0
50
0
0
70
0
10
0
0
0
0
% Q
% Arg:
80
0
0
0
0
10
80
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
80
0
0
0
0
0
10
0
% S
% Thr:
10
0
0
0
10
0
0
10
0
0
0
10
0
60
10
% T
% Val:
0
60
0
0
0
0
0
0
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
80
80
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _