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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TREH
All Species:
21.21
Human Site:
Y438
Identified Species:
51.85
UniProt:
O43280
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43280
NP_009111.2
583
66568
Y438
V
A
D
K
A
L
K
Y
L
E
D
N
R
I
L
Chimpanzee
Pan troglodytes
XP_522200
583
66612
Y438
V
A
D
K
A
L
K
Y
L
E
D
N
R
I
L
Rhesus Macaque
Macaca mulatta
XP_001094826
486
55076
A370
Q
Q
W
D
F
P
N
A
W
A
P
L
Q
D
L
Dog
Lupus familis
XP_546498
751
84039
Y564
V
V
D
K
V
L
K
Y
L
E
D
S
Q
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLT2
576
65383
Y435
V
A
D
K
A
L
K
Y
L
E
D
S
K
I
L
Rat
Rattus norvegicus
NP_001129613
576
65603
Y435
V
A
D
R
A
L
K
Y
L
E
D
N
K
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001336187
577
65839
Y436
M
S
D
Q
A
V
Q
Y
L
R
D
S
G
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2M2
596
67670
V462
S
E
K
I
S
A
S
V
M
A
Y
I
E
R
N
Honey Bee
Apis mellifera
A8J4S9
626
72798
V453
R
E
E
Y
V
S
K
V
L
K
Y
L
E
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195993
539
61740
D416
T
K
S
G
Q
Q
W
D
Y
P
N
A
W
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
80
61.5
N.A.
81.4
81.4
N.A.
N.A.
N.A.
N.A.
52.1
N.A.
42.1
42.4
N.A.
41.5
Protein Similarity:
100
99.1
81.4
68.1
N.A.
88.8
89
N.A.
N.A.
N.A.
N.A.
68.6
N.A.
60.9
61
N.A.
57.1
P-Site Identity:
100
100
6.6
73.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
40
N.A.
0
13.3
N.A.
0
P-Site Similarity:
100
100
13.3
86.6
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
80
N.A.
13.3
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
40
0
0
50
10
0
10
0
20
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
60
10
0
0
0
10
0
0
60
0
0
10
0
% D
% Glu:
0
20
10
0
0
0
0
0
0
50
0
0
20
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
10
0
50
0
% I
% Lys:
0
10
10
40
0
0
60
0
0
10
0
0
20
10
0
% K
% Leu:
0
0
0
0
0
50
0
0
70
0
0
20
0
0
70
% L
% Met:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
10
30
0
0
20
% N
% Pro:
0
0
0
0
0
10
0
0
0
10
10
0
0
10
10
% P
% Gln:
10
10
0
10
10
10
10
0
0
0
0
0
20
0
0
% Q
% Arg:
10
0
0
10
0
0
0
0
0
10
0
0
20
10
0
% R
% Ser:
10
10
10
0
10
10
10
0
0
0
0
30
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
50
10
0
0
20
10
0
20
0
0
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
10
0
10
0
0
0
10
0
0
% W
% Tyr:
0
0
0
10
0
0
0
60
10
0
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _