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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP3K13 All Species: 5.76
Human Site: S11 Identified Species: 10.56
UniProt: O43283 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43283 NP_004712.1 966 108296 S11 F Q E H L S C S S S P H L P F
Chimpanzee Pan troglodytes XP_001150116 966 108442 S11 F Q E H L S C S S S P H L P F
Rhesus Macaque Macaca mulatta XP_001105474 890 96134
Dog Lupus familis XP_848815 893 96248 R8 M A C L H E T R T P S P S F G
Cat Felis silvestris
Mouse Mus musculus Q1HKZ5 959 106968 C10 N P Q E H L S C S S L P H L P
Rat Rattus norvegicus Q63796 888 96289
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508287 535 59838
Chicken Gallus gallus
Frog Xenopus laevis A7J1T0 961 107551 E12 D I M A S P H E P L N W S S S
Zebra Danio Brachydanio rerio XP_696830 983 109314 N44 G D S I K K P N N N I S P Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95UN8 1161 128942 D10 S Q V S R G L D T T N M L P I
Honey Bee Apis mellifera XP_397605 895 101116 L10 T P A E T E T L S Q P E M Y K
Nematode Worm Caenorhab. elegans O01700 928 103465 P15 T T L D L V T P T S E E Q P G
Sea Urchin Strong. purpuratus XP_795085 943 105022 S11 P Q S M A T L S V T D C G S H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 50.8 50.8 N.A. 88.7 50 N.A. 46 N.A. 69.2 67.9 N.A. 23.7 35.9 27.4 37
Protein Similarity: 100 99.3 63.7 63.4 N.A. 93.2 63.4 N.A. 47.8 N.A. 78.9 76.3 N.A. 40 52.2 44 53.2
P-Site Identity: 100 100 0 0 N.A. 13.3 0 N.A. 0 N.A. 0 0 N.A. 20 13.3 20 13.3
P-Site Similarity: 100 100 0 6.6 N.A. 20 0 N.A. 0 N.A. 0 20 N.A. 33.3 20 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 8 8 0 0 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 8 0 0 0 16 8 0 0 0 8 0 0 0 % C
% Asp: 8 8 0 8 0 0 0 8 0 0 8 0 0 0 0 % D
% Glu: 0 0 16 16 0 16 0 8 0 0 8 16 0 0 0 % E
% Phe: 16 0 0 0 0 0 0 0 0 0 0 0 0 8 16 % F
% Gly: 8 0 0 0 0 8 0 0 0 0 0 0 8 0 16 % G
% His: 0 0 0 16 16 0 8 0 0 0 0 16 8 0 8 % H
% Ile: 0 8 0 8 0 0 0 0 0 0 8 0 0 0 8 % I
% Lys: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 8 % K
% Leu: 0 0 8 8 24 8 16 8 0 8 8 0 24 8 0 % L
% Met: 8 0 8 8 0 0 0 0 0 0 0 8 8 0 0 % M
% Asn: 8 0 0 0 0 0 0 8 8 8 16 0 0 0 0 % N
% Pro: 8 16 0 0 0 8 8 8 8 8 24 16 8 31 8 % P
% Gln: 0 31 8 0 0 0 0 0 0 8 0 0 8 8 0 % Q
% Arg: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 8 0 16 8 8 16 8 24 31 31 8 8 16 16 8 % S
% Thr: 16 8 0 0 8 8 24 0 24 16 0 0 0 0 0 % T
% Val: 0 0 8 0 0 8 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _