Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP3K13 All Species: 13.64
Human Site: S121 Identified Species: 25
UniProt: O43283 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43283 NP_004712.1 966 108296 S121 E D I K I Q F S R S G S G S G
Chimpanzee Pan troglodytes XP_001150116 966 108442 S121 E D I K I Q F S R S G S G S G
Rhesus Macaque Macaca mulatta XP_001105474 890 96134 Q115 D E V R L Q C Q S G S G F L E
Dog Lupus familis XP_848815 893 96248 S118 R L Q C Q S G S G F L E G L F
Cat Felis silvestris
Mouse Mus musculus Q1HKZ5 959 106968 S120 E D I K I Q F S R S G S G S G
Rat Rattus norvegicus Q63796 888 96289 Q113 R A D E V R L Q C Q S G S G F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508287 535 59838
Chicken Gallus gallus
Frog Xenopus laevis A7J1T0 961 107551 S122 E D I R I H F S R S R S G S G
Zebra Danio Brachydanio rerio XP_696830 983 109314 H154 E N G C P M E H S G D D T H H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95UN8 1161 128942 P120 D F V T D E D P L Q L N V S S
Honey Bee Apis mellifera XP_397605 895 101116 P120 G I L G C M R P V W T M L S K
Nematode Worm Caenorhab. elegans O01700 928 103465 D125 V E I E K S E D E L W E I P F
Sea Urchin Strong. purpuratus XP_795085 943 105022 N121 G C L K P V W N M I G K G N H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 50.8 50.8 N.A. 88.7 50 N.A. 46 N.A. 69.2 67.9 N.A. 23.7 35.9 27.4 37
Protein Similarity: 100 99.3 63.7 63.4 N.A. 93.2 63.4 N.A. 47.8 N.A. 78.9 76.3 N.A. 40 52.2 44 53.2
P-Site Identity: 100 100 6.6 13.3 N.A. 100 0 N.A. 0 N.A. 80 6.6 N.A. 6.6 6.6 6.6 20
P-Site Similarity: 100 100 40 13.3 N.A. 100 20 N.A. 0 N.A. 86.6 13.3 N.A. 33.3 13.3 20 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 8 0 16 8 0 8 0 8 0 0 0 0 0 0 % C
% Asp: 16 31 8 0 8 0 8 8 0 0 8 8 0 0 0 % D
% Glu: 39 16 0 16 0 8 16 0 8 0 0 16 0 0 8 % E
% Phe: 0 8 0 0 0 0 31 0 0 8 0 0 8 0 24 % F
% Gly: 16 0 8 8 0 0 8 0 8 16 31 16 47 8 31 % G
% His: 0 0 0 0 0 8 0 8 0 0 0 0 0 8 16 % H
% Ile: 0 8 39 0 31 0 0 0 0 8 0 0 8 0 0 % I
% Lys: 0 0 0 31 8 0 0 0 0 0 0 8 0 0 8 % K
% Leu: 0 8 16 0 8 0 8 0 8 8 16 0 8 16 0 % L
% Met: 0 0 0 0 0 16 0 0 8 0 0 8 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 8 0 0 0 8 0 8 0 % N
% Pro: 0 0 0 0 16 0 0 16 0 0 0 0 0 8 0 % P
% Gln: 0 0 8 0 8 31 0 16 0 16 0 0 0 0 0 % Q
% Arg: 16 0 0 16 0 8 8 0 31 0 8 0 0 0 0 % R
% Ser: 0 0 0 0 0 16 0 39 16 31 16 31 8 47 8 % S
% Thr: 0 0 0 8 0 0 0 0 0 0 8 0 8 0 0 % T
% Val: 8 0 16 0 8 8 0 0 8 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 8 8 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _