KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K13
All Species:
25.45
Human Site:
S376
Identified Species:
46.67
UniProt:
O43283
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43283
NP_004712.1
966
108296
S376
S
L
H
L
P
V
P
S
T
C
P
D
G
F
K
Chimpanzee
Pan troglodytes
XP_001150116
966
108442
S376
S
L
H
L
P
V
P
S
T
C
P
D
G
F
K
Rhesus Macaque
Macaca mulatta
XP_001105474
890
96134
D345
T
G
E
I
P
Y
K
D
V
D
S
S
A
I
I
Dog
Lupus familis
XP_848815
893
96248
S348
I
P
Y
K
D
V
D
S
S
A
I
I
W
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q1HKZ5
959
106968
S375
S
L
H
L
P
V
P
S
T
C
P
D
G
F
K
Rat
Rattus norvegicus
Q63796
888
96289
Y343
L
L
T
G
E
I
P
Y
K
D
V
D
S
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508287
535
59838
Chicken
Gallus gallus
Frog
Xenopus laevis
A7J1T0
961
107551
S379
S
L
H
L
P
V
P
S
T
C
P
D
G
F
K
Zebra Danio
Brachydanio rerio
XP_696830
983
109314
S427
S
L
H
L
P
V
P
S
T
C
P
D
G
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95UN8
1161
128942
K368
T
L
T
L
P
I
P
K
T
C
P
E
T
W
G
Honey Bee
Apis mellifera
XP_397605
895
101116
S350
I
W
G
V
G
N
N
S
L
H
L
P
I
P
A
Nematode Worm
Caenorhab. elegans
O01700
928
103465
K361
I
K
Q
C
L
S
Q
K
G
R
N
R
P
S
F
Sea Urchin
Strong. purpuratus
XP_795085
943
105022
S354
S
L
Q
L
P
I
P
S
T
C
P
E
G
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
50.8
50.8
N.A.
88.7
50
N.A.
46
N.A.
69.2
67.9
N.A.
23.7
35.9
27.4
37
Protein Similarity:
100
99.3
63.7
63.4
N.A.
93.2
63.4
N.A.
47.8
N.A.
78.9
76.3
N.A.
40
52.2
44
53.2
P-Site Identity:
100
100
6.6
13.3
N.A.
100
20
N.A.
0
N.A.
100
100
N.A.
46.6
6.6
0
80
P-Site Similarity:
100
100
20
26.6
N.A.
100
26.6
N.A.
0
N.A.
100
100
N.A.
73.3
13.3
0
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
16
% A
% Cys:
0
0
0
8
0
0
0
0
0
54
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
8
0
16
0
47
0
0
0
% D
% Glu:
0
0
8
0
8
0
0
0
0
0
0
16
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
47
8
% F
% Gly:
0
8
8
8
8
0
0
0
8
0
0
0
47
8
8
% G
% His:
0
0
39
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
24
0
0
8
0
24
0
0
0
0
8
8
8
8
8
% I
% Lys:
0
8
0
8
0
0
8
16
8
0
0
0
0
0
47
% K
% Leu:
8
62
0
54
8
0
0
0
8
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
0
8
0
0
0
0
% N
% Pro:
0
8
0
0
62
0
62
0
0
0
54
8
8
8
0
% P
% Gln:
0
0
16
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% R
% Ser:
47
0
0
0
0
8
0
62
8
0
8
8
8
16
0
% S
% Thr:
16
0
16
0
0
0
0
0
54
0
0
0
8
0
0
% T
% Val:
0
0
0
8
0
47
0
0
8
0
8
0
0
0
8
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
8
8
0
% W
% Tyr:
0
0
8
0
0
8
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _