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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP3K13 All Species: 10.61
Human Site: S598 Identified Species: 19.44
UniProt: O43283 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43283 NP_004712.1 966 108296 S598 R R G N S R G S H S D F A A I
Chimpanzee Pan troglodytes XP_001150116 966 108442 S598 R R G N S R G S H S D F A A I
Rhesus Macaque Macaca mulatta XP_001105474 890 96134 L532 K R N V P Q K L S P H S K R P
Dog Lupus familis XP_848815 893 96248 H535 V P Q K L S P H S K R P D I L
Cat Felis silvestris
Mouse Mus musculus Q1HKZ5 959 106968 S597 R R G N S R G S H S D F A A I
Rat Rattus norvegicus Q63796 888 96289 Q530 I K K R N V P Q K L S P H S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508287 535 59838 N177 G C L R P V W N I I G K A Y S
Chicken Gallus gallus
Frog Xenopus laevis A7J1T0 961 107551 R595 Y R S K P R H R R G N S K G S
Zebra Danio Brachydanio rerio XP_696830 983 109314 A618 P S V E P L P A P S P L S G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95UN8 1161 128942 T602 Q Q Q V A S L T P P P G L G I
Honey Bee Apis mellifera XP_397605 895 101116 K537 D C P Q S P I K A T M Y T Q L
Nematode Worm Caenorhab. elegans O01700 928 103465 E561 G Q Q T R R S E G A N P P K I
Sea Urchin Strong. purpuratus XP_795085 943 105022 R577 R R N N S H G R G S F C G K G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 50.8 50.8 N.A. 88.7 50 N.A. 46 N.A. 69.2 67.9 N.A. 23.7 35.9 27.4 37
Protein Similarity: 100 99.3 63.7 63.4 N.A. 93.2 63.4 N.A. 47.8 N.A. 78.9 76.3 N.A. 40 52.2 44 53.2
P-Site Identity: 100 100 6.6 0 N.A. 100 0 N.A. 6.6 N.A. 13.3 6.6 N.A. 6.6 6.6 13.3 40
P-Site Similarity: 100 100 20 6.6 N.A. 100 20 N.A. 13.3 N.A. 20 20 N.A. 33.3 26.6 33.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 8 8 8 0 0 31 24 0 % A
% Cys: 0 16 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 24 0 8 0 0 % D
% Glu: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 24 0 0 0 % F
% Gly: 16 0 24 0 0 0 31 0 16 8 8 8 8 24 8 % G
% His: 0 0 0 0 0 8 8 8 24 0 8 0 8 0 0 % H
% Ile: 8 0 0 0 0 0 8 0 8 8 0 0 0 8 39 % I
% Lys: 8 8 8 16 0 0 8 8 8 8 0 8 16 16 8 % K
% Leu: 0 0 8 0 8 8 8 8 0 8 0 8 8 0 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 16 31 8 0 0 8 0 0 16 0 0 0 0 % N
% Pro: 8 8 8 0 31 8 24 0 16 16 16 24 8 0 8 % P
% Gln: 8 16 24 8 0 8 0 8 0 0 0 0 0 8 0 % Q
% Arg: 31 47 0 16 8 39 0 16 8 0 8 0 0 8 0 % R
% Ser: 0 8 8 0 39 16 8 24 16 39 8 16 8 8 24 % S
% Thr: 0 0 0 8 0 0 0 8 0 8 0 0 8 0 0 % T
% Val: 8 0 8 16 0 16 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _