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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP3K13 All Species: 12.42
Human Site: S695 Identified Species: 22.78
UniProt: O43283 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43283 NP_004712.1 966 108296 S695 Q R Q L P G S S P D L I S T A
Chimpanzee Pan troglodytes XP_001150116 966 108442 S695 Q R Q L P G S S P D L I S T A
Rhesus Macaque Macaca mulatta XP_001105474 890 96134 H629 P A L R G L H H D L L L R K M
Dog Lupus familis XP_848815 893 96248 H632 P A L R G L H H D L L L R K M
Cat Felis silvestris
Mouse Mus musculus Q1HKZ5 959 106968 S694 Q R Q M P G S S P D L I S T A
Rat Rattus norvegicus Q63796 888 96289 L627 W D A S P P A L R G L H H D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508287 535 59838 Q274 M E Y C A H G Q L Y E V L R A
Chicken Gallus gallus
Frog Xenopus laevis A7J1T0 961 107551 S692 H R R M S G F S P D L L S S T
Zebra Danio Brachydanio rerio XP_696830 983 109314 A715 R Y F G P A A A L R S P Q T D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95UN8 1161 128942 N699 T N L T S Q P N T I I V L Q N
Honey Bee Apis mellifera XP_397605 895 101116 N634 K L S V N S L N K Q S L N K Q
Nematode Worm Caenorhab. elegans O01700 928 103465 G658 N K S T A V P G Q P V F F T R
Sea Urchin Strong. purpuratus XP_795085 943 105022 H674 N A K S R P G H V Q I V N E G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 50.8 50.8 N.A. 88.7 50 N.A. 46 N.A. 69.2 67.9 N.A. 23.7 35.9 27.4 37
Protein Similarity: 100 99.3 63.7 63.4 N.A. 93.2 63.4 N.A. 47.8 N.A. 78.9 76.3 N.A. 40 52.2 44 53.2
P-Site Identity: 100 100 6.6 6.6 N.A. 93.3 13.3 N.A. 6.6 N.A. 46.6 13.3 N.A. 0 0 6.6 0
P-Site Similarity: 100 100 13.3 13.3 N.A. 100 20 N.A. 13.3 N.A. 73.3 33.3 N.A. 20 33.3 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 8 0 16 8 16 8 0 0 0 0 0 0 31 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 16 31 0 0 0 8 8 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 8 0 0 8 0 % E
% Phe: 0 0 8 0 0 0 8 0 0 0 0 8 8 0 0 % F
% Gly: 0 0 0 8 16 31 16 8 0 8 0 0 0 0 8 % G
% His: 8 0 0 0 0 8 16 24 0 0 0 8 8 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 16 24 0 0 0 % I
% Lys: 8 8 8 0 0 0 0 0 8 0 0 0 0 24 0 % K
% Leu: 0 8 24 16 0 16 8 8 16 16 54 31 16 0 8 % L
% Met: 8 0 0 16 0 0 0 0 0 0 0 0 0 0 16 % M
% Asn: 16 8 0 0 8 0 0 16 0 0 0 0 16 0 8 % N
% Pro: 16 0 0 0 39 16 16 0 31 8 0 8 0 0 0 % P
% Gln: 24 0 24 0 0 8 0 8 8 16 0 0 8 8 8 % Q
% Arg: 8 31 8 16 8 0 0 0 8 8 0 0 16 8 8 % R
% Ser: 0 0 16 16 16 8 24 31 0 0 16 0 31 8 0 % S
% Thr: 8 0 0 16 0 0 0 0 8 0 0 0 0 39 8 % T
% Val: 0 0 0 8 0 8 0 0 8 0 8 24 0 0 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _