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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP3K13 All Species: 16.67
Human Site: S901 Identified Species: 30.56
UniProt: O43283 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43283 NP_004712.1 966 108296 S901 E I P I D I S S H S D G L S D
Chimpanzee Pan troglodytes XP_001150116 966 108442 S901 E I P I D I S S H S D G L S D
Rhesus Macaque Macaca mulatta XP_001105474 890 96134 S826 D D M C S Q G S E I P L D P P
Dog Lupus familis XP_848815 893 96248 S829 D D M C S Q G S E I P L D P P
Cat Felis silvestris
Mouse Mus musculus Q1HKZ5 959 106968 S894 E A P I E I S S H S D G L S D
Rat Rattus norvegicus Q63796 888 96289 M824 P D E R S D D M C S Q G S E I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508287 535 59838 F471 R E E V K K H F E K I K S E G
Chicken Gallus gallus
Frog Xenopus laevis A7J1T0 961 107551 I896 S Q T P E I P I E I S M Q S D
Zebra Danio Brachydanio rerio XP_696830 983 109314 T918 E I P I D I S T Q S D G L S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95UN8 1161 128942 T1026 Q E N S I L N T R R M Q D V Q
Honey Bee Apis mellifera XP_397605 895 101116 P831 N T S E Y S H P P S S Q S S T
Nematode Worm Caenorhab. elegans O01700 928 103465 L863 Q S T M M S S L E R S L E I G
Sea Urchin Strong. purpuratus XP_795085 943 105022 T878 G Q R A Q T A T P T S L S S V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 50.8 50.8 N.A. 88.7 50 N.A. 46 N.A. 69.2 67.9 N.A. 23.7 35.9 27.4 37
Protein Similarity: 100 99.3 63.7 63.4 N.A. 93.2 63.4 N.A. 47.8 N.A. 78.9 76.3 N.A. 40 52.2 44 53.2
P-Site Identity: 100 100 6.6 6.6 N.A. 86.6 13.3 N.A. 0 N.A. 20 86.6 N.A. 0 13.3 6.6 6.6
P-Site Similarity: 100 100 13.3 13.3 N.A. 93.3 13.3 N.A. 6.6 N.A. 26.6 93.3 N.A. 26.6 13.3 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 0 8 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 16 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 16 24 0 0 24 8 8 0 0 0 31 0 24 0 39 % D
% Glu: 31 16 16 8 16 0 0 0 39 0 0 0 8 16 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 16 0 0 0 0 39 0 0 16 % G
% His: 0 0 0 0 0 0 16 0 24 0 0 0 0 0 0 % H
% Ile: 0 24 0 31 8 39 0 8 0 24 8 0 0 8 8 % I
% Lys: 0 0 0 0 8 8 0 0 0 8 0 8 0 0 0 % K
% Leu: 0 0 0 0 0 8 0 8 0 0 0 31 31 0 0 % L
% Met: 0 0 16 8 8 0 0 8 0 0 8 8 0 0 0 % M
% Asn: 8 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 31 8 0 0 8 8 16 0 16 0 0 16 16 % P
% Gln: 16 16 0 0 8 16 0 0 8 0 8 16 8 0 8 % Q
% Arg: 8 0 8 8 0 0 0 0 8 16 0 0 0 0 0 % R
% Ser: 8 8 8 8 24 16 39 39 0 47 31 0 31 54 0 % S
% Thr: 0 8 16 0 0 8 0 24 0 8 0 0 0 0 8 % T
% Val: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _