Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP3K13 All Species: 16.06
Human Site: S903 Identified Species: 29.44
UniProt: O43283 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43283 NP_004712.1 966 108296 S903 P I D I S S H S D G L S D K E
Chimpanzee Pan troglodytes XP_001150116 966 108442 S903 P I D I S S H S D G L S D K E
Rhesus Macaque Macaca mulatta XP_001105474 890 96134 I828 M C S Q G S E I P L D P P P S
Dog Lupus familis XP_848815 893 96248 I831 M C S Q G S E I P L D P P A S
Cat Felis silvestris
Mouse Mus musculus Q1HKZ5 959 106968 S896 P I E I S S H S D G L S D K E
Rat Rattus norvegicus Q63796 888 96289 S826 E R S D D M C S Q G S E I P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508287 535 59838 K473 E V K K H F E K I K S E G T C
Chicken Gallus gallus
Frog Xenopus laevis A7J1T0 961 107551 I898 T P E I P I E I S M Q S D G L
Zebra Danio Brachydanio rerio XP_696830 983 109314 S920 P I D I S T Q S D G L S D K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95UN8 1161 128942 R1028 N S I L N T R R M Q D V Q P H
Honey Bee Apis mellifera XP_397605 895 101116 S833 S E Y S H P P S S Q S S T L E
Nematode Worm Caenorhab. elegans O01700 928 103465 R865 T M M S S L E R S L E I G A T
Sea Urchin Strong. purpuratus XP_795085 943 105022 T880 R A Q T A T P T S L S S V A I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 50.8 50.8 N.A. 88.7 50 N.A. 46 N.A. 69.2 67.9 N.A. 23.7 35.9 27.4 37
Protein Similarity: 100 99.3 63.7 63.4 N.A. 93.2 63.4 N.A. 47.8 N.A. 78.9 76.3 N.A. 40 52.2 44 53.2
P-Site Identity: 100 100 6.6 6.6 N.A. 93.3 13.3 N.A. 0 N.A. 20 86.6 N.A. 0 20 6.6 6.6
P-Site Similarity: 100 100 6.6 6.6 N.A. 100 13.3 N.A. 6.6 N.A. 26.6 93.3 N.A. 20 20 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 0 0 0 0 0 0 0 0 24 0 % A
% Cys: 0 16 0 0 0 0 8 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 24 8 8 0 0 0 31 0 24 0 39 0 0 % D
% Glu: 16 8 16 0 0 0 39 0 0 0 8 16 0 0 39 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 16 0 0 0 0 39 0 0 16 8 0 % G
% His: 0 0 0 0 16 0 24 0 0 0 0 0 0 0 8 % H
% Ile: 0 31 8 39 0 8 0 24 8 0 0 8 8 0 8 % I
% Lys: 0 0 8 8 0 0 0 8 0 8 0 0 0 31 0 % K
% Leu: 0 0 0 8 0 8 0 0 0 31 31 0 0 8 16 % L
% Met: 16 8 8 0 0 8 0 0 8 8 0 0 0 0 0 % M
% Asn: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 31 8 0 0 8 8 16 0 16 0 0 16 16 24 0 % P
% Gln: 0 0 8 16 0 0 8 0 8 16 8 0 8 0 0 % Q
% Arg: 8 8 0 0 0 0 8 16 0 0 0 0 0 0 0 % R
% Ser: 8 8 24 16 39 39 0 47 31 0 31 54 0 0 16 % S
% Thr: 16 0 0 8 0 24 0 8 0 0 0 0 8 8 8 % T
% Val: 0 8 0 0 0 0 0 0 0 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _