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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K13
All Species:
9.39
Human Site:
T776
Identified Species:
17.22
UniProt:
O43283
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43283
NP_004712.1
966
108296
T776
N
A
Q
S
S
E
K
T
E
E
N
E
F
S
G
Chimpanzee
Pan troglodytes
XP_001150116
966
108442
T776
N
A
Q
S
S
E
K
T
E
E
N
E
F
S
G
Rhesus Macaque
Macaca mulatta
XP_001105474
890
96134
L707
G
P
G
E
G
V
G
L
L
G
T
G
R
E
G
Dog
Lupus familis
XP_848815
893
96248
L710
G
P
G
D
V
V
G
L
L
G
T
G
R
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q1HKZ5
959
106968
T774
N
A
Q
G
S
E
R
T
G
A
N
G
F
S
G
Rat
Rattus norvegicus
Q63796
888
96289
G705
P
P
P
P
V
G
P
G
E
G
V
G
L
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508287
535
59838
A352
M
S
F
A
G
T
V
A
W
M
A
P
E
V
I
Chicken
Gallus gallus
Frog
Xenopus laevis
A7J1T0
961
107551
T775
E
D
Y
E
K
L
E
T
G
G
E
Q
F
S
S
Zebra Danio
Brachydanio rerio
XP_696830
983
109314
D795
Y
S
L
L
S
T
N
D
G
T
P
P
A
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95UN8
1161
128942
A878
T
A
R
D
C
D
D
A
E
E
A
F
E
G
G
Honey Bee
Apis mellifera
XP_397605
895
101116
N712
R
L
I
S
S
I
D
N
G
N
C
D
D
I
I
Nematode Worm
Caenorhab. elegans
O01700
928
103465
D737
S
P
T
P
Y
D
N
D
F
E
N
A
E
S
F
Sea Urchin
Strong. purpuratus
XP_795085
943
105022
M757
R
L
G
G
T
D
V
M
G
L
K
S
S
Y
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
50.8
50.8
N.A.
88.7
50
N.A.
46
N.A.
69.2
67.9
N.A.
23.7
35.9
27.4
37
Protein Similarity:
100
99.3
63.7
63.4
N.A.
93.2
63.4
N.A.
47.8
N.A.
78.9
76.3
N.A.
40
52.2
44
53.2
P-Site Identity:
100
100
6.6
6.6
N.A.
66.6
13.3
N.A.
0
N.A.
20
13.3
N.A.
26.6
13.3
20
0
P-Site Similarity:
100
100
6.6
6.6
N.A.
73.3
13.3
N.A.
13.3
N.A.
33.3
20
N.A.
40
20
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
0
8
0
0
0
16
0
8
16
8
8
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
8
0
16
0
24
16
16
0
0
0
8
8
0
0
% D
% Glu:
8
0
0
16
0
24
8
0
31
31
8
16
24
16
0
% E
% Phe:
0
0
8
0
0
0
0
0
8
0
0
8
31
0
8
% F
% Gly:
16
0
24
16
16
8
16
8
39
31
0
31
0
8
54
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
8
0
0
0
0
0
0
0
8
24
% I
% Lys:
0
0
0
0
8
0
16
0
0
0
8
0
0
0
8
% K
% Leu:
0
16
8
8
0
8
0
16
16
8
0
0
8
8
0
% L
% Met:
8
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% M
% Asn:
24
0
0
0
0
0
16
8
0
8
31
0
0
0
0
% N
% Pro:
8
31
8
16
0
0
8
0
0
0
8
16
0
0
0
% P
% Gln:
0
0
24
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
16
0
8
0
0
0
8
0
0
0
0
0
16
0
0
% R
% Ser:
8
16
0
24
39
0
0
0
0
0
0
8
8
47
8
% S
% Thr:
8
0
8
0
8
16
0
31
0
8
16
0
0
0
0
% T
% Val:
0
0
0
0
16
16
16
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
8
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _