Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP3K13 All Species: 10.3
Human Site: Y641 Identified Species: 18.89
UniProt: O43283 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43283 NP_004712.1 966 108296 Y641 H N S L Q Q Q Y Q Q P P P A M
Chimpanzee Pan troglodytes XP_001150116 966 108442 Y641 H N S L Q Q Q Y Q Q S P P A M
Rhesus Macaque Macaca mulatta XP_001105474 890 96134 R575 P S P G R S R R G K T R H R K
Dog Lupus familis XP_848815 893 96248 T578 G R S R R G K T R H R K A S A
Cat Felis silvestris
Mouse Mus musculus Q1HKZ5 959 106968 Y640 H N P L Q Q Q Y Q Q I P P A Q
Rat Rattus norvegicus Q63796 888 96289 S573 A P P S P G R S R R G K T R H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508287 535 59838 K220 Q G A V F L G K F R A E E V A
Chicken Gallus gallus
Frog Xenopus laevis A7J1T0 961 107551 P638 P P V T P C S P Y H E T S Q V
Zebra Danio Brachydanio rerio XP_696830 983 109314 P661 E F P G V L K P N S G P P E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95UN8 1161 128942 K645 N N N I G N C K A I T T T I T
Honey Bee Apis mellifera XP_397605 895 101116 P580 G C G I N S S P R S S P H R E
Nematode Worm Caenorhab. elegans O01700 928 103465 W604 F S Q D S G M W S A G A G S C
Sea Urchin Strong. purpuratus XP_795085 943 105022 A620 S D I R K P D A E T S R F I K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 50.8 50.8 N.A. 88.7 50 N.A. 46 N.A. 69.2 67.9 N.A. 23.7 35.9 27.4 37
Protein Similarity: 100 99.3 63.7 63.4 N.A. 93.2 63.4 N.A. 47.8 N.A. 78.9 76.3 N.A. 40 52.2 44 53.2
P-Site Identity: 100 93.3 0 6.6 N.A. 80 0 N.A. 0 N.A. 0 13.3 N.A. 6.6 6.6 0 0
P-Site Similarity: 100 93.3 26.6 33.3 N.A. 80 20 N.A. 20 N.A. 6.6 20 N.A. 26.6 20 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 0 0 8 8 8 8 8 8 24 16 % A
% Cys: 0 8 0 0 0 8 8 0 0 0 0 0 0 0 8 % C
% Asp: 0 8 0 8 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 8 0 8 8 8 8 16 % E
% Phe: 8 8 0 0 8 0 0 0 8 0 0 0 8 0 0 % F
% Gly: 16 8 8 16 8 24 8 0 8 0 24 0 8 0 0 % G
% His: 24 0 0 0 0 0 0 0 0 16 0 0 16 0 8 % H
% Ile: 0 0 8 16 0 0 0 0 0 8 8 0 0 16 0 % I
% Lys: 0 0 0 0 8 0 16 16 0 8 0 16 0 0 16 % K
% Leu: 0 0 0 24 0 16 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 16 % M
% Asn: 8 31 8 0 8 8 0 0 8 0 0 0 0 0 0 % N
% Pro: 16 16 31 0 16 8 0 24 0 0 8 39 31 0 0 % P
% Gln: 8 0 8 0 24 24 24 0 24 24 0 0 0 8 8 % Q
% Arg: 0 8 0 16 16 0 16 8 24 16 8 16 0 24 0 % R
% Ser: 8 16 24 8 8 16 16 8 8 16 24 0 8 16 0 % S
% Thr: 0 0 0 8 0 0 0 8 0 8 16 16 16 0 8 % T
% Val: 0 0 8 8 8 0 0 0 0 0 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 24 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _