KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K13
All Species:
15.45
Human Site:
Y845
Identified Species:
28.33
UniProt:
O43283
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43283
NP_004712.1
966
108296
Y845
C
I
S
S
C
Q
S
Y
S
T
F
S
S
E
N
Chimpanzee
Pan troglodytes
XP_001150116
966
108442
Y845
C
I
S
S
C
Q
S
Y
S
T
F
S
S
E
N
Rhesus Macaque
Macaca mulatta
XP_001105474
890
96134
Q776
P
Q
S
L
N
M
R
Q
S
L
S
T
F
S
S
Dog
Lupus familis
XP_848815
893
96248
Q779
P
Q
G
L
N
M
R
Q
S
R
S
T
F
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q1HKZ5
959
106968
S843
Q
S
Y
S
T
F
S
S
E
N
F
S
V
S
D
Rat
Rattus norvegicus
Q63796
888
96289
G774
P
S
Q
R
W
P
Q
G
P
N
M
R
Q
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508287
535
59838
K421
D
G
F
K
I
L
M
K
Q
T
W
Q
S
K
P
Chicken
Gallus gallus
Frog
Xenopus laevis
A7J1T0
961
107551
Y844
G
M
S
T
C
Q
S
Y
S
T
F
S
S
E
N
Zebra Danio
Brachydanio rerio
XP_696830
983
109314
Y864
C
M
S
S
F
Q
S
Y
S
T
F
S
S
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95UN8
1161
128942
R947
R
Q
N
S
T
T
S
R
K
S
S
V
T
F
Q
Honey Bee
Apis mellifera
XP_397605
895
101116
S781
D
E
E
G
E
D
P
S
Y
T
Y
N
Y
S
L
Nematode Worm
Caenorhab. elegans
O01700
928
103465
D806
V
D
E
E
N
A
N
D
V
D
L
T
S
S
M
Sea Urchin
Strong. purpuratus
XP_795085
943
105022
E826
A
P
D
H
S
S
D
E
D
T
L
T
L
Q
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
50.8
50.8
N.A.
88.7
50
N.A.
46
N.A.
69.2
67.9
N.A.
23.7
35.9
27.4
37
Protein Similarity:
100
99.3
63.7
63.4
N.A.
93.2
63.4
N.A.
47.8
N.A.
78.9
76.3
N.A.
40
52.2
44
53.2
P-Site Identity:
100
100
13.3
6.6
N.A.
26.6
0
N.A.
13.3
N.A.
80
86.6
N.A.
13.3
6.6
6.6
13.3
P-Site Similarity:
100
100
26.6
20
N.A.
33.3
0
N.A.
26.6
N.A.
93.3
93.3
N.A.
33.3
20
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
24
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
8
8
0
0
8
8
8
8
8
0
0
0
0
8
% D
% Glu:
0
8
16
8
8
0
0
8
8
0
0
0
0
31
0
% E
% Phe:
0
0
8
0
8
8
0
0
0
0
39
0
16
8
0
% F
% Gly:
8
8
8
8
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
8
8
0
0
0
0
8
0
% K
% Leu:
0
0
0
16
0
8
0
0
0
8
16
0
8
0
16
% L
% Met:
0
16
0
0
0
16
8
0
0
0
8
0
0
0
8
% M
% Asn:
0
0
8
0
24
0
8
0
0
16
0
8
0
0
39
% N
% Pro:
24
8
0
0
0
8
8
0
8
0
0
0
0
0
8
% P
% Gln:
8
24
8
0
0
31
8
16
8
0
0
8
8
8
8
% Q
% Arg:
8
0
0
8
0
0
16
8
0
8
0
8
0
0
0
% R
% Ser:
0
16
39
39
8
8
47
16
47
8
24
39
47
47
16
% S
% Thr:
0
0
0
8
16
8
0
0
0
54
0
31
8
0
0
% T
% Val:
8
0
0
0
0
0
0
0
8
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
31
8
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _