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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPINT2
All Species:
19.7
Human Site:
S237
Identified Species:
48.15
UniProt:
O43291
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43291
NP_066925.1
252
28228
S237
R
A
L
R
T
V
W
S
S
G
D
D
K
E
Q
Chimpanzee
Pan troglodytes
XP_524249
414
45350
S366
S
S
S
D
S
S
S
S
S
S
D
S
D
T
D
Rhesus Macaque
Macaca mulatta
XP_001106508
252
28108
S237
R
A
L
R
T
V
W
S
S
G
D
D
K
E
Q
Dog
Lupus familis
XP_853537
252
28034
S237
R
T
L
R
T
V
W
S
S
G
D
D
K
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU03
252
27896
S237
R
A
L
R
T
V
W
S
T
A
D
D
K
E
Q
Rat
Rattus norvegicus
NP_001076018
250
27449
S235
R
A
L
R
T
V
W
S
T
A
D
D
K
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518665
481
53346
S446
K
K
R
R
K
G
S
S
R
R
R
R
H
P
P
Chicken
Gallus gallus
XP_421130
467
52878
N446
R
Q
P
T
T
A
T
N
S
T
L
S
T
T
E
Frog
Xenopus laevis
NP_001089642
315
34504
D301
V
L
H
S
L
M
E
D
A
A
E
T
K
T
I
Zebra Danio
Brachydanio rerio
NP_001070718
431
47981
I408
N
S
H
P
H
F
R
I
L
D
D
K
E
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.1
96
77.3
N.A.
70.6
68.2
N.A.
23.9
20.5
21.8
24.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
49.2
97.2
84.5
N.A.
80.5
80.1
N.A.
32.4
32.1
35.8
37.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
93.3
N.A.
86.6
86.6
N.A.
13.3
20
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
93.3
N.A.
93.3
93.3
N.A.
20
33.3
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
40
0
0
0
10
0
0
10
30
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
10
0
10
70
50
10
0
10
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
10
0
10
60
10
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
30
0
0
0
0
0
% G
% His:
0
0
20
0
10
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% I
% Lys:
10
10
0
0
10
0
0
0
0
0
0
10
60
0
0
% K
% Leu:
0
10
50
0
10
0
0
0
10
0
10
0
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
10
0
0
0
0
0
0
0
0
0
10
10
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
50
% Q
% Arg:
60
0
10
60
0
0
10
0
10
10
10
10
0
0
0
% R
% Ser:
10
20
10
10
10
10
20
70
50
10
0
20
0
0
0
% S
% Thr:
0
10
0
10
60
0
10
0
20
10
0
10
10
30
0
% T
% Val:
10
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _