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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPINT2
All Species:
9.09
Human Site:
Y250
Identified Species:
22.22
UniProt:
O43291
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43291
NP_066925.1
252
28228
Y250
E
Q
L
V
K
N
T
Y
V
L
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_524249
414
45350
A379
T
D
V
K
S
H
A
A
G
S
K
Q
H
E
S
Rhesus Macaque
Macaca mulatta
XP_001106508
252
28108
Y250
E
Q
L
V
K
N
T
Y
V
L
_
_
_
_
_
Dog
Lupus familis
XP_853537
252
28034
Y250
E
Q
L
V
K
N
T
Y
V
L
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU03
252
27896
C250
E
Q
L
V
K
N
T
C
V
L
_
_
_
_
_
Rat
Rattus norvegicus
NP_001076018
250
27449
C248
E
Q
L
V
K
N
T
C
V
L
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518665
481
53346
A459
P
P
P
P
P
T
G
A
S
S
T
V
S
T
A
Chicken
Gallus gallus
XP_421130
467
52878
F459
T
E
D
T
E
H
L
F
Y
N
G
A
T
K
P
Frog
Xenopus laevis
NP_001089642
315
34504
Zebra Danio
Brachydanio rerio
NP_001070718
431
47981
P421
E
L
L
P
A
E
E
P
V
S
Y
E
K
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.1
96
77.3
N.A.
70.6
68.2
N.A.
23.9
20.5
21.8
24.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
49.2
97.2
84.5
N.A.
80.5
80.1
N.A.
32.4
32.1
35.8
37.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
90
90
N.A.
0
0
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
90
90
N.A.
0
33.3
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
20
0
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
60
10
0
0
10
10
10
0
0
0
0
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
10
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
20
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
50
0
0
0
0
0
10
0
10
10
0
% K
% Leu:
0
10
60
0
0
0
10
0
0
50
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
50
0
0
0
10
0
0
0
0
0
% N
% Pro:
10
10
10
20
10
0
0
10
0
0
0
0
0
0
20
% P
% Gln:
0
50
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
0
10
30
0
0
10
0
10
% S
% Thr:
20
0
0
10
0
10
50
0
0
0
10
0
10
10
0
% T
% Val:
0
0
10
50
0
0
0
0
60
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
30
10
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
50
50
50
50
50
% _