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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPAA1 All Species: 25.76
Human Site: T45 Identified Species: 47.22
UniProt: O43292 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43292 NP_003792.1 621 67623 T45 A L V F P P L T Q R T Y M S E
Chimpanzee Pan troglodytes XP_001155503 621 67574 T45 A L V F P P L T Q R T Y M S E
Rhesus Macaque Macaca mulatta XP_001088872 621 67614 T45 A L V F P P L T Q R T Y M S E
Dog Lupus familis XP_532350 699 76490 T96 A L A F P P L T Q R T Y M S E
Cat Felis silvestris
Mouse Mus musculus Q9WTK3 621 67930 T45 A L A F P P L T Q R T Y M S E
Rat Rattus norvegicus NP_001004240 621 67946 T45 A L A F P P L T Q R T Y M S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521791 271 29170
Chicken Gallus gallus
Frog Xenopus laevis NP_001083412 615 68437 T45 G L A F H P F T L R S Y I S E
Zebra Danio Brachydanio rerio XP_683113 515 57119 L12 T Q S F F Q K L P F P D E N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572273 674 75292 N47 C L A L P E F N H G T Y L S E
Honey Bee Apis mellifera XP_624738 532 61389 Y30 Q P L C Y F L Y I S G I I W M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202328 661 73328 N45 V L A F T P L N E K T Y F S E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39012 614 69203 D45 S I A I L P M D G Q Y R R T Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.8 80.5 N.A. 91.3 91.7 N.A. 37.3 N.A. 66.6 51.8 N.A. 32.3 31.2 N.A. 33.8
Protein Similarity: 100 99.8 99.3 84.4 N.A. 94.6 94.1 N.A. 39.7 N.A. 81.1 64.7 N.A. 47.9 50.2 N.A. 54.1
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 0 N.A. 53.3 6.6 N.A. 40 6.6 N.A. 53.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 0 N.A. 66.6 20 N.A. 46.6 20 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 0 54 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 8 0 0 0 8 0 70 % E
% Phe: 0 0 0 70 8 8 16 0 0 8 0 0 8 0 0 % F
% Gly: 8 0 0 0 0 0 0 0 8 8 8 0 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 8 0 8 0 0 0 0 8 0 0 8 16 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 8 % K
% Leu: 0 70 8 8 8 0 62 8 8 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 47 0 8 % M
% Asn: 0 0 0 0 0 0 0 16 0 0 0 0 0 8 0 % N
% Pro: 0 8 0 0 54 70 0 0 8 0 8 0 0 0 0 % P
% Gln: 8 8 0 0 0 8 0 0 47 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 54 0 8 8 0 0 % R
% Ser: 8 0 8 0 0 0 0 0 0 8 8 0 0 70 0 % S
% Thr: 8 0 0 0 8 0 0 54 0 0 62 0 0 8 0 % T
% Val: 8 0 24 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 8 0 0 8 0 0 8 70 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _