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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGFB1I1
All Species:
27.27
Human Site:
Y451
Identified Species:
54.55
UniProt:
O43294
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43294
NP_001035919.1
461
49814
Y451
Q
E
R
A
G
K
P
Y
C
Q
P
C
F
L
K
Chimpanzee
Pan troglodytes
XP_001159426
434
46626
P427
A
G
K
P
Y
C
Q
P
C
F
L
K
L
F
G
Rhesus Macaque
Macaca mulatta
XP_001113103
461
49794
Y451
Q
E
R
A
G
K
P
Y
C
Q
P
C
F
L
K
Dog
Lupus familis
XP_547052
461
49726
Y451
Q
E
R
A
G
K
P
Y
C
Q
P
C
F
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q62219
461
50082
Y451
Q
E
R
A
S
K
P
Y
C
Q
P
C
F
L
K
Rat
Rattus norvegicus
Q99PD6
461
50104
Y451
Q
E
R
A
S
K
P
Y
C
Q
P
C
F
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514315
225
25219
P218
A
D
K
P
Y
C
H
P
C
F
L
K
L
F
G
Chicken
Gallus gallus
P49024
559
61224
Y549
K
E
Q
N
D
K
P
Y
C
Q
N
C
F
L
K
Frog
Xenopus laevis
Q2TCH4
506
55983
Y496
R
E
H
D
E
K
P
Y
C
Q
A
C
Y
A
R
Zebra Danio
Brachydanio rerio
Q6P7E4
419
45574
K412
K
K
D
K
P
L
C
K
S
H
A
F
S
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724183
557
61985
Y547
K
E
Q
K
D
K
P
Y
C
H
T
C
F
D
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
N406
F
C
H
K
C
Y
N
N
T
Y
A
L
T
P
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.1
99.5
93.2
N.A.
91.3
91.5
N.A.
45.3
43.4
43
22.7
N.A.
40.5
N.A.
36
N.A.
Protein Similarity:
100
94.1
99.5
95
N.A.
93
92.8
N.A.
47
55.9
56.7
34
N.A.
55.4
N.A.
51.8
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
93.3
N.A.
6.6
66.6
46.6
0
N.A.
53.3
N.A.
0
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
93.3
N.A.
20
80
66.6
13.3
N.A.
66.6
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
42
0
0
0
0
0
0
25
0
0
9
9
% A
% Cys:
0
9
0
0
9
17
9
0
84
0
0
67
0
0
0
% C
% Asp:
0
9
9
9
17
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
67
0
0
9
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
17
0
9
59
17
0
% F
% Gly:
0
9
0
0
25
0
0
0
0
0
0
0
0
0
17
% G
% His:
0
0
17
0
0
0
9
0
0
17
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
25
9
17
25
0
67
0
9
0
0
0
17
0
0
59
% K
% Leu:
0
0
0
0
0
9
0
0
0
0
17
9
17
42
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
9
9
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
17
9
0
67
17
0
0
42
0
0
17
0
% P
% Gln:
42
0
17
0
0
0
9
0
0
59
0
0
0
0
0
% Q
% Arg:
9
0
42
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
0
0
17
0
0
0
9
0
0
0
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
9
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
9
0
67
0
9
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _