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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA12A
All Species:
17.27
Human Site:
S19
Identified Species:
42.22
UniProt:
O43301
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43301
NP_079291.2
675
74978
S19
P
R
E
T
A
P
T
S
A
Y
S
S
P
A
R
Chimpanzee
Pan troglodytes
XP_529348
668
74301
R19
S
A
Y
S
S
P
A
R
S
L
G
D
T
G
I
Rhesus Macaque
Macaca mulatta
XP_001095628
812
89841
S156
S
L
E
T
A
P
T
S
A
Y
S
S
P
A
R
Dog
Lupus familis
XP_544034
744
81944
S88
F
A
E
T
A
P
T
S
A
Y
S
S
P
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0U4
675
74853
T19
G
P
R
E
T
A
P
T
S
T
Y
S
S
P
A
Rat
Rattus norvegicus
NP_001100915
675
74812
T19
G
P
R
E
T
A
P
T
S
A
Y
S
S
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512019
674
75027
S18
P
R
K
M
A
P
T
S
A
Y
S
S
P
A
K
Chicken
Gallus gallus
XP_421779
670
74732
S18
A
V
S
T
S
A
Y
S
S
P
A
K
S
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036151
691
77339
T23
G
E
D
K
S
D
S
T
S
P
S
G
S
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780658
1340
145466
N687
K
N
N
S
A
L
A
N
S
E
P
T
T
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
82.6
88.3
N.A.
96.4
96.8
N.A.
90.6
88.4
N.A.
62.3
N.A.
N.A.
N.A.
N.A.
26.4
Protein Similarity:
100
98.5
82.8
89.7
N.A.
98.2
98.5
N.A.
95.4
94.2
N.A.
78.7
N.A.
N.A.
N.A.
N.A.
36.7
P-Site Identity:
100
6.6
86.6
86.6
N.A.
6.6
6.6
N.A.
80
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
86.6
86.6
N.A.
20
20
N.A.
93.3
33.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
0
0
50
30
20
0
40
10
10
0
0
40
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
10
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
10
30
20
0
0
0
0
0
10
0
0
0
0
10
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
30
0
0
0
0
0
0
0
0
0
10
10
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
10
0
10
10
0
0
0
0
0
0
0
10
0
0
10
% K
% Leu:
0
10
0
0
0
10
0
0
0
10
0
0
0
10
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
20
20
0
0
0
50
20
0
0
20
10
0
40
40
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
20
20
0
0
0
0
10
0
0
0
0
0
0
30
% R
% Ser:
20
0
10
20
30
0
10
50
60
0
50
60
40
0
0
% S
% Thr:
0
0
0
40
20
0
40
30
0
10
0
10
20
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
10
0
0
40
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _