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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPA12A All Species: 10.61
Human Site: T15 Identified Species: 25.93
UniProt: O43301 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43301 NP_079291.2 675 74978 T15 G S D G P R E T A P T S A Y S
Chimpanzee Pan troglodytes XP_529348 668 74301 S15 T A P T S A Y S S P A R S L G
Rhesus Macaque Macaca mulatta XP_001095628 812 89841 T152 E L D Y S L E T A P T S A Y S
Dog Lupus familis XP_544034 744 81944 T84 P R L L F A E T A P T S A Y S
Cat Felis silvestris
Mouse Mus musculus Q8K0U4 675 74853 E15 G G D A G P R E T A P T S T Y
Rat Rattus norvegicus NP_001100915 675 74812 E15 G G D A G P R E T A P T S A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512019 674 75027 M14 G S P G P R K M A P T S A Y S
Chicken Gallus gallus XP_421779 670 74732 T14 G V P H A V S T S A Y S S P A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001036151 691 77339 K19 L Q V P G E D K S D S T S P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780658 1340 145466 S683 G R L C K N N S A L A N S E P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 82.6 88.3 N.A. 96.4 96.8 N.A. 90.6 88.4 N.A. 62.3 N.A. N.A. N.A. N.A. 26.4
Protein Similarity: 100 98.5 82.8 89.7 N.A. 98.2 98.5 N.A. 95.4 94.2 N.A. 78.7 N.A. N.A. N.A. N.A. 36.7
P-Site Identity: 100 6.6 66.6 60 N.A. 13.3 13.3 N.A. 80 20 N.A. 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 33.3 66.6 60 N.A. 26.6 26.6 N.A. 86.6 40 N.A. 40 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 20 10 20 0 0 50 30 20 0 40 10 10 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 40 0 0 0 10 0 0 10 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 10 30 20 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 60 20 0 20 30 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 0 10 10 0 0 0 0 0 0 0 % K
% Leu: 10 10 20 10 0 10 0 0 0 10 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 10 0 0 0 0 10 0 0 0 % N
% Pro: 10 0 30 10 20 20 0 0 0 50 20 0 0 20 10 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 20 0 0 0 20 20 0 0 0 0 10 0 0 0 % R
% Ser: 0 20 0 0 20 0 10 20 30 0 10 50 60 0 50 % S
% Thr: 10 0 0 10 0 0 0 40 20 0 40 30 0 10 0 % T
% Val: 0 10 10 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 10 0 0 0 10 0 0 40 20 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _