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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA12A
All Species:
8.79
Human Site:
T45
Identified Species:
21.48
UniProt:
O43301
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43301
NP_079291.2
675
74978
T45
P
S
H
I
V
N
D
T
D
S
N
V
S
E
Q
Chimpanzee
Pan troglodytes
XP_529348
668
74301
Q45
T
D
S
N
V
S
E
Q
Q
S
F
L
V
V
V
Rhesus Macaque
Macaca mulatta
XP_001095628
812
89841
T182
P
S
H
I
V
N
D
T
D
S
N
V
S
E
Q
Dog
Lupus familis
XP_544034
744
81944
A114
P
S
H
I
V
N
D
A
D
T
N
V
S
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0U4
675
74853
D45
S
P
S
H
I
L
N
D
A
D
P
V
S
E
Q
Rat
Rattus norvegicus
NP_001100915
675
74812
D45
S
P
S
H
I
L
N
D
A
D
P
V
S
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512019
674
75027
S44
P
S
H
A
V
N
D
S
D
P
N
V
P
E
Q
Chicken
Gallus gallus
XP_421779
670
74732
E44
I
V
K
D
S
D
A
E
D
A
V
E
Q
L
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036151
691
77339
T49
T
P
S
P
S
P
R
T
E
V
R
P
R
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780658
1340
145466
P713
S
L
P
A
T
P
I
P
V
S
P
I
S
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
82.6
88.3
N.A.
96.4
96.8
N.A.
90.6
88.4
N.A.
62.3
N.A.
N.A.
N.A.
N.A.
26.4
Protein Similarity:
100
98.5
82.8
89.7
N.A.
98.2
98.5
N.A.
95.4
94.2
N.A.
78.7
N.A.
N.A.
N.A.
N.A.
36.7
P-Site Identity:
100
13.3
100
86.6
N.A.
26.6
26.6
N.A.
73.3
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
33.3
100
93.3
N.A.
40
40
N.A.
80
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
0
10
10
20
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
10
40
20
50
20
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
10
10
0
0
10
0
70
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
40
20
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
30
20
0
10
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
20
0
0
0
0
0
10
0
20
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
40
20
0
0
0
40
0
0
0
0
% N
% Pro:
40
30
10
10
0
20
0
10
0
10
30
10
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
10
0
0
0
10
0
60
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
10
0
10
0
0
% R
% Ser:
30
40
40
0
20
10
0
10
0
40
0
0
60
0
10
% S
% Thr:
20
0
0
0
10
0
0
30
0
10
0
0
0
0
0
% T
% Val:
0
10
0
0
50
0
0
0
10
10
10
60
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _