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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC14L5 All Species: 10.91
Human Site: S453 Identified Species: 21.82
UniProt: O43304 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43304 NP_055507.1 696 78942 S453 K F L I Y S G S N Y Q G P G G
Chimpanzee Pan troglodytes XP_001155788 703 80307 N454 K F L I Y A G N D Y Q G P G G
Rhesus Macaque Macaca mulatta XP_001098962 775 87125 S532 K F L I Y S G S N Y Q G P G G
Dog Lupus familis XP_547140 695 78724 S453 K F L I Y S G S N Y Q G P G G
Cat Felis silvestris
Mouse Mus musculus Q8R0F9 403 46035 W164 G L S L R H L W K P A V E V Y
Rat Rattus norvegicus Q99MS0 403 46148 W164 G L G L K H L W K P A V E A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414710 694 78680 N446 K F L I Y S G N N Y Q G P G G
Frog Xenopus laevis NP_001087870 715 81309 N466 K F L I Y A G N D Y Q G P G G
Zebra Danio Brachydanio rerio NP_957392 697 79632 N448 K F L I Y A G N D Y Q G P G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VMD6 659 75661 V415 F P I A W T I V S A F I D E H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q03606 719 81064 S466 K F M V S G G S G G D L K E E
Sea Urchin Strong. purpuratus XP_783768 1178 131796 K931 K F L I Y G G K N Y M E S G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.2 87.3 91 N.A. 21.8 21.9 N.A. N.A. 75.1 66.1 63.7 N.A. 41.5 N.A. 45 32
Protein Similarity: 100 84 88.1 94.9 N.A. 35.6 37.6 N.A. N.A. 85.1 83 80.3 N.A. 61.2 N.A. 64.8 43.6
P-Site Identity: 100 80 100 100 N.A. 0 0 N.A. N.A. 93.3 80 80 N.A. 0 N.A. 26.6 66.6
P-Site Similarity: 100 100 100 100 N.A. 6.6 6.6 N.A. N.A. 100 100 100 N.A. 26.6 N.A. 40 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 25 0 0 0 9 17 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 25 0 9 0 9 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 9 17 17 9 % E
% Phe: 9 75 0 0 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 17 0 9 0 0 17 75 0 9 9 0 59 0 67 67 % G
% His: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 9 67 0 0 9 0 0 0 0 9 0 0 0 % I
% Lys: 75 0 0 0 9 0 0 9 17 0 0 0 9 0 0 % K
% Leu: 0 17 67 17 0 0 17 0 0 0 0 9 0 0 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 34 42 0 0 0 0 0 0 % N
% Pro: 0 9 0 0 0 0 0 0 0 17 0 0 59 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 % Q
% Arg: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 9 0 9 34 0 34 9 0 0 0 9 0 0 % S
% Thr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 9 0 0 0 9 0 0 0 17 0 9 0 % V
% Trp: 0 0 0 0 9 0 0 17 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 67 0 0 0 0 67 0 0 0 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _