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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HISPPD1 All Species: 33.33
Human Site: S264 Identified Species: 73.33
UniProt: O43314 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43314 NP_056031.2 1243 140407 S264 A H A E A R K S P A L D G K V
Chimpanzee Pan troglodytes XP_001137685 1243 140418 S264 A H A E A R K S P A L D G K V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546000 1330 149506 S351 A H A E A R K S P A L D G K V
Cat Felis silvestris
Mouse Mus musculus Q6ZQB6 1129 128411 T208 N V Y I Y Y P T S A G G G S Q
Rat Rattus norvegicus P0C644 1434 159600 S277 A H A E A R K S P A L D G K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505793 1285 145199 S327 A H A E A R K S P A L D G K V
Chicken Gallus gallus XP_424859 1229 138729 S274 A H A E A R K S P A L D G K V
Frog Xenopus laevis Q5XHF8 1131 128702 Y211 S A E D H N V Y I Y Y P T S A
Zebra Danio Brachydanio rerio XP_002663536 1233 138707 S231 A H A E A R K S P A L D G K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VR59 1696 188659 S287 A H A E A R K S P A L D G K V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91309 1323 150102 A239 A H A E A R K A P G L D G K V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 91.5 N.A. 85.7 57.8 N.A. 85.5 86.2 76.6 78.1 N.A. 45.1 N.A. 43.7 N.A.
Protein Similarity: 100 99.9 N.A. 92.7 N.A. 88.1 68.1 N.A. 89.8 91.7 82.6 85.9 N.A. 56.7 N.A. 60.3 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 13.3 100 N.A. 100 100 0 100 N.A. 100 N.A. 86.6 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 20 100 N.A. 100 100 13.3 100 N.A. 100 N.A. 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 82 10 82 0 82 0 0 10 0 82 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 82 0 0 0 % D
% Glu: 0 0 10 82 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 10 10 91 0 0 % G
% His: 0 82 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 82 0 0 0 0 0 0 82 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 82 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 10 0 82 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 82 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 0 73 10 0 0 0 0 19 0 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % T
% Val: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 82 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 10 10 0 10 0 10 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _