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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HISPPD1
All Species:
18.79
Human Site:
S721
Identified Species:
41.33
UniProt:
O43314
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43314
NP_056031.2
1243
140407
S721
K
N
G
R
Y
D
I
S
K
I
P
D
I
Y
D
Chimpanzee
Pan troglodytes
XP_001137685
1243
140418
S721
K
N
G
R
Y
D
I
S
K
I
P
D
I
Y
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546000
1330
149506
S808
K
N
G
R
Y
D
I
S
K
I
P
D
I
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQB6
1129
128411
S613
N
M
N
G
L
L
D
S
D
S
D
S
L
S
S
Rat
Rattus norvegicus
P0C644
1434
159600
S735
K
S
G
R
Y
D
I
S
K
I
P
D
I
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505793
1285
145199
L770
M
L
R
R
W
S
K
L
E
K
D
F
K
T
K
Chicken
Gallus gallus
XP_424859
1229
138729
H703
S
A
D
I
Q
L
Y
H
S
E
T
L
E
L
M
Frog
Xenopus laevis
Q5XHF8
1131
128702
N616
M
V
K
S
A
N
M
N
G
L
L
D
S
D
S
Zebra Danio
Brachydanio rerio
XP_002663536
1233
138707
S688
K
N
G
R
Y
N
I
S
K
I
P
D
I
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR59
1696
188659
D753
F
D
I
S
K
I
P
D
I
Y
D
C
I
K
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91309
1323
150102
D739
S
K
I
P
D
I
Y
D
N
I
K
Y
D
M
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
91.5
N.A.
85.7
57.8
N.A.
85.5
86.2
76.6
78.1
N.A.
45.1
N.A.
43.7
N.A.
Protein Similarity:
100
99.9
N.A.
92.7
N.A.
88.1
68.1
N.A.
89.8
91.7
82.6
85.9
N.A.
56.7
N.A.
60.3
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
6.6
93.3
N.A.
6.6
0
6.6
93.3
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
13.3
100
N.A.
20
0
33.3
100
N.A.
13.3
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
10
10
0
10
37
10
19
10
0
28
55
10
10
46
% D
% Glu:
0
0
0
0
0
0
0
0
10
10
0
0
10
0
10
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
46
10
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
19
10
0
19
46
0
10
55
0
0
55
0
0
% I
% Lys:
46
10
10
0
10
0
10
0
46
10
10
0
10
10
10
% K
% Leu:
0
10
0
0
10
19
0
10
0
10
10
10
10
10
0
% L
% Met:
19
10
0
0
0
0
10
0
0
0
0
0
0
10
10
% M
% Asn:
10
37
10
0
0
19
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
10
0
0
0
46
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
55
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
19
10
0
19
0
10
0
55
10
10
0
10
10
10
19
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
46
0
19
0
0
10
0
10
0
46
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _