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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HISPPD1
All Species:
17.88
Human Site:
Y556
Identified Species:
39.33
UniProt:
O43314
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43314
NP_056031.2
1243
140407
Y556
L
L
R
L
H
S
T
Y
R
H
D
L
K
I
Y
Chimpanzee
Pan troglodytes
XP_001137685
1243
140418
Y556
L
L
R
L
H
S
T
Y
R
H
D
L
K
I
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546000
1330
149506
Y643
L
L
R
L
H
S
T
Y
R
H
D
L
K
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQB6
1129
128411
N454
L
M
E
L
G
Q
N
N
D
S
E
I
E
E
N
Rat
Rattus norvegicus
P0C644
1434
159600
F570
L
L
R
L
H
S
T
F
R
H
D
L
K
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505793
1285
145199
G609
G
D
Y
A
G
F
P
G
C
G
L
L
R
L
H
Chicken
Gallus gallus
XP_424859
1229
138729
C542
E
L
G
R
A
F
R
C
M
Y
P
G
G
Q
G
Frog
Xenopus laevis
Q5XHF8
1131
128702
E457
I
A
R
Q
L
L
V
E
L
G
Q
N
N
D
S
Zebra Danio
Brachydanio rerio
XP_002663536
1233
138707
Y523
L
L
R
L
H
S
T
Y
R
H
D
L
K
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR59
1696
188659
F585
L
L
R
L
H
S
T
F
R
H
D
L
K
I
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91309
1323
150102
Y565
F
L
R
L
H
S
T
Y
R
H
D
L
K
I
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
91.5
N.A.
85.7
57.8
N.A.
85.5
86.2
76.6
78.1
N.A.
45.1
N.A.
43.7
N.A.
Protein Similarity:
100
99.9
N.A.
92.7
N.A.
88.1
68.1
N.A.
89.8
91.7
82.6
85.9
N.A.
56.7
N.A.
60.3
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
13.3
93.3
N.A.
6.6
6.6
6.6
100
N.A.
93.3
N.A.
93.3
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
40
100
N.A.
26.6
13.3
13.3
100
N.A.
100
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
10
0
64
0
0
10
0
% D
% Glu:
10
0
10
0
0
0
0
10
0
0
10
0
10
10
0
% E
% Phe:
10
0
0
0
0
19
0
19
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
19
0
0
10
0
19
0
10
10
0
10
% G
% His:
0
0
0
0
64
0
0
0
0
64
0
0
0
0
10
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
10
0
64
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
64
0
0
% K
% Leu:
64
73
0
73
10
10
0
0
10
0
10
73
0
10
0
% L
% Met:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
10
0
0
0
10
10
0
10
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
10
0
10
0
0
0
0
10
0
0
10
0
% Q
% Arg:
0
0
73
10
0
0
10
0
64
0
0
0
10
0
0
% R
% Ser:
0
0
0
0
0
64
0
0
0
10
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
64
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
46
0
10
0
0
0
0
64
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _