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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAX4
All Species:
12.73
Human Site:
S259
Identified Species:
25.45
UniProt:
O43316
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43316
NP_006184.2
350
37833
S259
G
I
I
S
A
Q
Q
S
P
G
S
V
P
T
A
Chimpanzee
Pan troglodytes
Q2VL62
341
36320
E250
G
L
E
K
G
A
L
E
Q
E
A
K
Y
G
Q
Rhesus Macaque
Macaca mulatta
Q2VL61
341
36390
E250
G
L
E
K
G
V
L
E
Q
E
A
K
Y
G
Q
Dog
Lupus familis
XP_539387
302
33168
T212
P
S
A
S
P
G
T
T
F
A
Q
Q
S
P
G
Cat
Felis silvestris
Mouse
Mus musculus
P32115
349
37990
S259
G
I
I
S
A
Q
Q
S
P
G
S
V
P
S
A
Rat
Rattus norvegicus
O88436
349
38466
S259
G
I
I
S
A
Q
Q
S
P
G
S
V
P
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P55166
339
36196
E248
G
L
E
K
S
S
L
E
Q
E
A
K
Y
S
Q
Frog
Xenopus laevis
P55864
422
46668
A328
A
L
T
N
S
Y
S
A
L
P
P
M
P
S
F
Zebra Danio
Brachydanio rerio
P26630
437
48407
A346
A
L
T
N
T
Y
S
A
L
P
P
M
P
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09082
427
45497
S312
A
S
S
T
S
G
T
S
S
A
A
H
S
P
V
Honey Bee
Apis mellifera
XP_394648
597
62909
S444
G
G
S
S
G
G
G
S
S
T
A
P
P
A
A
Nematode Worm
Caenorhab. elegans
NP_001024570
455
51043
G361
Y
S
F
G
I
A
N
G
F
S
M
A
P
Y
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.4
29.7
68.8
N.A.
80
79.7
N.A.
N.A.
29.4
38.6
38.2
N.A.
31.1
28.9
36.2
N.A.
Protein Similarity:
100
42
42.2
73.1
N.A.
84.5
85.7
N.A.
N.A.
41.7
50
49.4
N.A.
44.7
37.1
48.5
N.A.
P-Site Identity:
100
6.6
6.6
6.6
N.A.
93.3
93.3
N.A.
N.A.
6.6
6.6
6.6
N.A.
6.6
33.3
6.6
N.A.
P-Site Similarity:
100
20
20
13.3
N.A.
100
100
N.A.
N.A.
33.3
46.6
40
N.A.
26.6
40
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
9
0
25
17
0
17
0
17
42
9
0
9
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
25
0
0
0
0
25
0
25
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
17
0
0
0
0
0
17
% F
% Gly:
59
9
0
9
25
25
9
9
0
25
0
0
0
17
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
25
25
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
25
0
0
0
0
0
0
0
25
0
0
0
% K
% Leu:
0
42
0
0
0
0
25
0
17
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
17
0
0
0
% M
% Asn:
0
0
0
17
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
9
0
0
0
25
17
17
9
59
17
9
% P
% Gln:
0
0
0
0
0
25
25
0
25
0
9
9
0
0
25
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
25
17
42
25
9
17
42
17
9
25
0
17
42
0
% S
% Thr:
0
0
17
9
9
0
17
9
0
9
0
0
0
9
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
25
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
17
0
0
0
0
0
0
25
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _