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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K7
All Species:
10.61
Human Site:
S361
Identified Species:
21.21
UniProt:
O43318
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43318
NP_003179.1
606
67196
S361
K
N
Q
A
K
Q
Q
S
E
S
G
R
L
S
L
Chimpanzee
Pan troglodytes
XP_001160138
472
51727
I239
I
G
G
P
A
F
R
I
M
W
A
V
H
N
G
Rhesus Macaque
Macaca mulatta
XP_001099744
609
67549
S361
K
N
Q
A
K
Q
Q
S
E
S
G
R
L
S
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62073
579
64209
N334
T
S
N
K
S
D
T
N
M
E
Q
V
P
A
T
Rat
Rattus norvegicus
P0C8E4
606
67182
S361
K
N
Q
A
K
Q
Q
S
D
S
G
R
L
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507638
595
66386
Q350
M
K
N
Q
A
K
Q
Q
S
D
T
G
R
L
S
Chicken
Gallus gallus
XP_001233491
604
67342
K351
S
K
L
A
Q
Q
M
K
N
T
A
K
Q
P
G
Frog
Xenopus laevis
Q7T2V3
1005
111856
I502
P
S
G
F
E
H
K
I
T
V
Q
A
S
P
M
Zebra Danio
Brachydanio rerio
NP_001018586
544
61104
K310
D
Y
T
C
T
S
N
K
N
D
I
N
M
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3Q6
678
75656
T344
K
T
T
T
S
S
M
T
E
N
T
S
S
T
S
Honey Bee
Apis mellifera
XP_397248
510
58111
F277
M
T
T
L
S
Q
F
F
N
E
H
L
E
P
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795629
463
51420
G230
I
M
W
A
V
H
N
G
R
R
P
P
L
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
99.5
N.A.
N.A.
95
99
N.A.
91.4
91.7
21.9
70.6
N.A.
34.5
41.4
N.A.
39.9
Protein Similarity:
100
75.7
99.5
N.A.
N.A.
95
99.3
N.A.
93.7
93.7
35.7
77.8
N.A.
52.2
58.7
N.A.
51.4
P-Site Identity:
100
0
100
N.A.
N.A.
0
93.3
N.A.
6.6
13.3
0
0
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
13.3
100
N.A.
N.A.
20
100
N.A.
13.3
33.3
26.6
6.6
N.A.
33.3
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
42
17
0
0
0
0
0
17
9
0
9
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
9
0
0
9
17
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
25
17
0
0
9
9
0
% E
% Phe:
0
0
0
9
0
9
9
9
0
0
0
0
0
0
0
% F
% Gly:
0
9
17
0
0
0
0
9
0
0
25
9
0
0
17
% G
% His:
0
0
0
0
0
17
0
0
0
0
9
0
9
0
9
% H
% Ile:
17
0
0
0
0
0
0
17
0
0
9
0
0
9
0
% I
% Lys:
34
17
0
9
25
9
9
17
0
0
0
9
0
0
0
% K
% Leu:
0
0
9
9
0
0
0
0
0
0
0
9
34
9
25
% L
% Met:
17
9
0
0
0
0
17
0
17
0
0
0
9
0
9
% M
% Asn:
0
25
17
0
0
0
17
9
25
9
0
9
0
9
0
% N
% Pro:
9
0
0
9
0
0
0
0
0
0
9
9
9
25
0
% P
% Gln:
0
0
25
9
9
42
34
9
0
0
17
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
9
9
0
25
9
0
9
% R
% Ser:
9
17
0
0
25
17
0
25
9
25
0
9
17
25
17
% S
% Thr:
9
17
25
9
9
0
9
9
9
9
17
0
0
9
9
% T
% Val:
0
0
0
0
9
0
0
0
0
9
0
17
0
0
9
% V
% Trp:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _