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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K7
All Species:
17.27
Human Site:
S389
Identified Species:
34.55
UniProt:
O43318
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43318
NP_003179.1
606
67196
S389
T
S
E
G
K
R
M
S
A
D
M
S
E
I
E
Chimpanzee
Pan troglodytes
XP_001160138
472
51727
W267
E
S
L
M
T
R
C
W
S
K
D
P
S
Q
R
Rhesus Macaque
Macaca mulatta
XP_001099744
609
67549
S389
T
S
E
G
K
R
M
S
A
D
M
S
E
I
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62073
579
64209
E362
N
Q
A
K
Q
Q
S
E
S
G
R
L
S
L
G
Rat
Rattus norvegicus
P0C8E4
606
67182
S389
T
S
E
G
K
R
M
S
A
D
M
S
E
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507638
595
66386
S378
P
S
E
S
K
R
M
S
A
D
M
S
E
I
E
Chicken
Gallus gallus
XP_001233491
604
67342
V379
S
V
E
S
L
S
D
V
R
E
A
K
R
M
S
Frog
Xenopus laevis
Q7T2V3
1005
111856
I530
P
P
G
S
P
L
I
I
P
R
L
R
A
I
R
Zebra Danio
Brachydanio rerio
NP_001018586
544
61104
G338
Y
K
P
K
G
I
S
G
Q
S
L
S
R
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3Q6
678
75656
T372
N
P
L
F
Y
M
V
T
N
R
W
D
A
I
P
Honey Bee
Apis mellifera
XP_397248
510
58111
T305
N
H
V
S
K
N
D
T
L
D
V
T
D
S
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795629
463
51420
T258
S
S
P
V
H
S
S
T
K
D
Q
Q
K
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
99.5
N.A.
N.A.
95
99
N.A.
91.4
91.7
21.9
70.6
N.A.
34.5
41.4
N.A.
39.9
Protein Similarity:
100
75.7
99.5
N.A.
N.A.
95
99.3
N.A.
93.7
93.7
35.7
77.8
N.A.
52.2
58.7
N.A.
51.4
P-Site Identity:
100
13.3
100
N.A.
N.A.
0
100
N.A.
86.6
6.6
6.6
6.6
N.A.
6.6
13.3
N.A.
13.3
P-Site Similarity:
100
20
100
N.A.
N.A.
26.6
100
N.A.
86.6
26.6
20
13.3
N.A.
20
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
34
0
9
0
17
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
17
0
0
50
9
9
9
0
0
% D
% Glu:
9
0
42
0
0
0
0
9
0
9
0
0
34
0
34
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
25
9
0
0
9
0
9
0
0
0
9
9
% G
% His:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
9
9
9
0
0
0
0
0
50
0
% I
% Lys:
0
9
0
17
42
0
0
0
9
9
0
9
9
0
0
% K
% Leu:
0
0
17
0
9
9
0
0
9
0
17
9
0
9
0
% L
% Met:
0
0
0
9
0
9
34
0
0
0
34
0
0
9
9
% M
% Asn:
25
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% N
% Pro:
17
17
17
0
9
0
0
0
9
0
0
9
0
0
9
% P
% Gln:
0
9
0
0
9
9
0
0
9
0
9
9
0
9
0
% Q
% Arg:
0
0
0
0
0
42
0
0
9
17
9
9
17
9
17
% R
% Ser:
17
50
0
34
0
17
25
34
17
9
0
42
17
9
17
% S
% Thr:
25
0
0
0
9
0
0
25
0
0
0
9
0
0
0
% T
% Val:
0
9
9
9
0
0
9
9
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% W
% Tyr:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _