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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K7
All Species:
16.97
Human Site:
T502
Identified Species:
33.94
UniProt:
O43318
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43318
NP_003179.1
606
67196
T502
S
I
P
M
A
Y
L
T
L
D
H
Q
L
Q
P
Chimpanzee
Pan troglodytes
XP_001160138
472
51727
P380
G
S
S
V
E
S
L
P
P
T
S
E
G
K
R
Rhesus Macaque
Macaca mulatta
XP_001099744
609
67549
A502
S
D
N
S
I
P
M
A
Y
L
T
L
D
H
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62073
579
64209
T475
S
I
P
M
A
Y
L
T
L
D
H
Q
L
Q
P
Rat
Rattus norvegicus
P0C8E4
606
67182
T502
S
I
P
M
A
Y
L
T
L
D
H
Q
L
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507638
595
66386
T491
S
I
P
M
A
Y
L
T
L
D
H
Q
L
Q
P
Chicken
Gallus gallus
XP_001233491
604
67342
N492
G
K
T
N
G
S
D
N
S
I
P
M
A
Y
L
Frog
Xenopus laevis
Q7T2V3
1005
111856
T643
P
Y
S
Q
S
Y
L
T
L
P
V
Q
S
D
H
Zebra Danio
Brachydanio rerio
NP_001018586
544
61104
C451
Q
L
Q
P
L
A
P
C
P
N
S
K
E
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3Q6
678
75656
N485
N
G
L
L
S
H
A
N
G
W
Q
A
R
D
E
Honey Bee
Apis mellifera
XP_397248
510
58111
E418
Q
T
C
E
R
S
K
E
I
F
E
E
H
K
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795629
463
51420
S371
P
S
P
I
P
Y
P
S
P
M
T
S
L
S
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
99.5
N.A.
N.A.
95
99
N.A.
91.4
91.7
21.9
70.6
N.A.
34.5
41.4
N.A.
39.9
Protein Similarity:
100
75.7
99.5
N.A.
N.A.
95
99.3
N.A.
93.7
93.7
35.7
77.8
N.A.
52.2
58.7
N.A.
51.4
P-Site Identity:
100
6.6
6.6
N.A.
N.A.
100
100
N.A.
100
0
33.3
0
N.A.
0
0
N.A.
20
P-Site Similarity:
100
26.6
13.3
N.A.
N.A.
100
100
N.A.
100
0
40
20
N.A.
26.6
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
34
9
9
9
0
0
0
9
9
0
0
% A
% Cys:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
9
0
0
34
0
0
9
17
0
% D
% Glu:
0
0
0
9
9
0
0
9
0
0
9
17
9
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
17
9
0
0
9
0
0
0
9
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
34
0
9
9
9
% H
% Ile:
0
34
0
9
9
0
0
0
9
9
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
9
0
0
0
0
9
0
17
0
% K
% Leu:
0
9
9
9
9
0
50
0
42
9
0
9
42
0
9
% L
% Met:
0
0
0
34
0
0
9
0
0
9
0
9
0
0
9
% M
% Asn:
9
0
9
9
0
0
0
17
0
9
0
0
0
0
0
% N
% Pro:
17
0
42
9
9
9
17
9
25
9
9
0
0
0
34
% P
% Gln:
17
0
9
9
0
0
0
0
0
0
9
42
0
34
17
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
9
% R
% Ser:
42
17
17
9
17
25
0
9
9
0
17
9
9
17
0
% S
% Thr:
0
9
9
0
0
0
0
42
0
9
17
0
0
0
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% W
% Tyr:
0
9
0
0
0
50
0
0
9
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _