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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHH
All Species:
7.58
Human Site:
S252
Identified Species:
18.52
UniProt:
O43323
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43323
NP_066382.1
396
43577
S252
R
D
L
Q
R
R
A
S
F
V
A
V
E
T
E
Chimpanzee
Pan troglodytes
XP_526034
411
45281
V256
R
E
P
H
R
L
R
V
F
Q
V
I
E
T
Q
Rhesus Macaque
Macaca mulatta
XP_001099775
299
32987
D201
A
R
R
L
R
A
G
D
S
V
L
A
P
G
G
Dog
Lupus familis
XP_861428
434
47259
V251
R
D
D
G
A
K
K
V
F
Y
V
I
E
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61488
396
43524
S252
R
D
L
Q
R
R
A
S
F
V
A
V
E
T
E
Rat
Rattus norvegicus
Q63673
437
47612
V252
R
D
E
G
A
K
K
V
F
Y
V
I
E
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q91035
425
46456
L254
R
M
D
S
S
R
K
L
F
Y
V
I
E
T
R
Frog
Xenopus laevis
Q91610
396
44068
T251
R
N
P
Y
K
T
A
T
F
V
L
I
E
A
E
Zebra Danio
Brachydanio rerio
Q90419
416
46558
Q254
H
D
P
T
T
R
R
Q
F
I
V
I
E
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02936
471
52132
N311
R
N
L
E
Q
M
Q
N
F
V
Q
L
H
T
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.1
74.7
58.7
N.A.
96.4
57.2
N.A.
N.A.
58.3
63.6
55
N.A.
45
N.A.
N.A.
N.A.
Protein Similarity:
100
67.6
75
70.7
N.A.
97.9
70
N.A.
N.A.
70.5
77.2
70.4
N.A.
57.9
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
13.3
33.3
N.A.
100
33.3
N.A.
N.A.
33.3
40
33.3
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
13.3
46.6
N.A.
100
46.6
N.A.
N.A.
40
66.6
46.6
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
20
10
30
0
0
0
20
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
50
20
0
0
0
0
10
0
0
0
0
0
0
10
% D
% Glu:
0
10
10
10
0
0
0
0
0
0
0
0
80
0
30
% E
% Phe:
0
0
0
0
0
0
0
0
90
0
0
0
0
0
0
% F
% Gly:
0
0
0
20
0
0
10
0
0
0
0
0
0
10
10
% G
% His:
10
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
60
0
0
0
% I
% Lys:
0
0
0
0
10
20
30
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
30
10
0
10
0
10
0
0
20
10
0
0
0
% L
% Met:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
30
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
20
10
0
10
10
0
10
10
0
0
0
10
% Q
% Arg:
80
10
10
0
40
40
20
0
0
0
0
0
0
0
30
% R
% Ser:
0
0
0
10
10
0
0
20
10
0
0
0
0
0
10
% S
% Thr:
0
0
0
10
10
10
0
10
0
0
0
0
0
80
0
% T
% Val:
0
0
0
0
0
0
0
30
0
50
50
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
30
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _