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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EEF1E1 All Species: 34.85
Human Site: Y139 Identified Species: 69.7
UniProt: O43324 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43324 NP_004271.1 174 19811 Y139 T V Q E K E K Y L N V S R W F
Chimpanzee Pan troglodytes XP_001166169 164 18457 R130 G L H R F I I R K L K H T E V
Rhesus Macaque Macaca mulatta XP_001086399 174 19806 Y139 T V Q E K E K Y L N V S R W F
Dog Lupus familis XP_535882 174 19869 Y139 T V Q E K E K Y L N V S R W F
Cat Felis silvestris
Mouse Mus musculus Q9D1M4 174 19840 Y139 T V Q E K E K Y L N V S R W F
Rat Rattus norvegicus NP_001099576 174 19824 Y139 T V Q E K E K Y L N V S R W F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514132 174 19806 Y139 T V Q E K E K Y L N V S R W F
Chicken Gallus gallus XP_418953 229 25072 Y194 T V Q E K E I Y L N V S R W F
Frog Xenopus laevis NP_001088441 174 19442 Y139 S I Q E K E T Y I N V S R W F
Zebra Danio Brachydanio rerio XP_692806 173 19906 N139 Q E K E C Y L N V S R W F D H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_660194 179 19961 Y140 S P V D K E V Y L N L S R W F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787842 85 9928 L51 E K E K Y L H L S R W F D H V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.5 99.4 95.4 N.A. 88.5 87.9 N.A. 84.4 55 65.5 63.2 N.A. 29 N.A. N.A. 28.1
Protein Similarity: 100 81 100 98.2 N.A. 93 93 N.A. 93 65.5 80.4 78.7 N.A. 46.3 N.A. N.A. 35.6
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 100 93.3 73.3 6.6 N.A. 60 N.A. N.A. 0
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 100 93.3 93.3 26.6 N.A. 80 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 0 0 0 0 9 9 0 % D
% Glu: 9 9 9 75 0 75 0 0 0 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 9 0 0 0 0 0 0 9 9 0 75 % F
% Gly: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 9 0 0 0 9 0 0 0 0 9 0 9 9 % H
% Ile: 0 9 0 0 0 9 17 0 9 0 0 0 0 0 0 % I
% Lys: 0 9 9 9 75 0 50 0 9 0 9 0 0 0 0 % K
% Leu: 0 9 0 0 0 9 9 9 67 9 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 75 0 0 0 0 0 % N
% Pro: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 67 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 9 0 0 0 9 0 9 9 0 75 0 0 % R
% Ser: 17 0 0 0 0 0 0 0 9 9 0 75 0 0 0 % S
% Thr: 59 0 0 0 0 0 9 0 0 0 0 0 9 0 0 % T
% Val: 0 59 9 0 0 0 9 0 9 0 67 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 9 0 75 0 % W
% Tyr: 0 0 0 0 9 9 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _