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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MSI1 All Species: 21.52
Human Site: Y39 Identified Species: 39.44
UniProt: O43347 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43347 NP_002433.1 362 39125 Y39 T Q E G L R E Y F G Q F G E V
Chimpanzee Pan troglodytes XP_001162046 324 34904 Q27 F I G G L S W Q T S P D S L R
Rhesus Macaque Macaca mulatta Q28521 320 34202 F23 L F I G G L S F E T T D E S L
Dog Lupus familis XP_854252 351 38019 Y39 T Q E G L R E Y F G Q F G E V
Cat Felis silvestris
Mouse Mus musculus Q61474 362 39101 Y39 T Q E G L R E Y F G Q F G E V
Rat Rattus norvegicus Q8K3P4 362 39115 Y39 T Q E G L R E Y F G Q F G E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506312 349 37295 K39 S L R D Y F S K F G E I R E C
Chicken Gallus gallus Q5ZI72 301 33425
Frog Xenopus laevis Q98SJ2 360 39210 K43 V V D C V I M K D K T T N Q S
Zebra Danio Brachydanio rerio NP_001013534 330 35800 Q33 G L S W Q T T Q E G L K D Y F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVE5 369 40069 Y48 S P E S L R D Y F G R Y G D I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22037 346 36325 F42 T D D L M R E F Y S Q F G E I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q99383 534 59631 Y178 T E D N L R E Y F G K Y G T V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.3 30.1 96.6 N.A. 99.4 99.7 N.A. 65.4 31.4 32 80.9 N.A. 52.8 N.A. 28.1 N.A.
Protein Similarity: 100 75.4 44.4 96.6 N.A. 99.7 99.7 N.A. 72.3 45.8 45.5 87 N.A. 64.7 N.A. 42.5 N.A.
P-Site Identity: 100 13.3 6.6 100 N.A. 100 100 N.A. 20 0 0 6.6 N.A. 46.6 N.A. 46.6 N.A.
P-Site Similarity: 100 13.3 20 100 N.A. 100 100 N.A. 33.3 0 20 6.6 N.A. 86.6 N.A. 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 60 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 8 24 8 0 0 8 0 8 0 0 16 8 8 0 % D
% Glu: 0 8 39 0 0 0 47 0 16 0 8 0 8 47 0 % E
% Phe: 8 8 0 0 0 8 0 16 54 0 0 39 0 0 8 % F
% Gly: 8 0 8 47 8 0 0 0 0 62 0 0 54 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 0 8 0 0 0 0 0 8 0 0 16 % I
% Lys: 0 0 0 0 0 0 0 16 0 8 8 8 0 0 0 % K
% Leu: 8 16 0 8 54 8 0 0 0 0 8 0 0 8 8 % L
% Met: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % P
% Gln: 0 31 0 0 8 0 0 16 0 0 39 0 0 8 0 % Q
% Arg: 0 0 8 0 0 54 0 0 0 0 8 0 8 0 8 % R
% Ser: 16 0 8 8 0 8 16 0 0 16 0 0 8 8 8 % S
% Thr: 47 0 0 0 0 8 8 0 8 8 16 8 0 8 0 % T
% Val: 8 8 0 0 8 0 0 0 0 0 0 0 0 0 39 % V
% Trp: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 47 8 0 0 16 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _