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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF3
All Species:
32.73
Human Site:
S131
Identified Species:
55.38
UniProt:
O43395
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43395
NP_004689.1
683
77529
S131
E
V
I
P
G
P
P
S
E
S
P
G
M
L
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101105
683
77496
S131
E
V
I
P
G
P
P
S
E
S
P
G
M
L
T
Dog
Lupus familis
XP_860581
685
77562
S131
E
V
I
P
G
P
P
S
E
S
P
G
M
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q922U1
683
77436
S131
E
V
I
P
G
P
P
S
E
S
P
G
M
L
T
Rat
Rattus norvegicus
NP_001102029
637
72177
S131
E
V
I
P
G
P
P
S
E
S
P
G
M
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509322
682
76176
D130
E
G
V
P
R
P
V
D
E
N
P
G
L
L
T
Chicken
Gallus gallus
Q5ZJ85
684
77367
S131
E
V
I
P
G
P
P
S
E
S
P
G
M
L
T
Frog
Xenopus laevis
NP_001085273
679
76844
S131
E
V
I
P
G
P
P
S
E
S
P
G
M
L
T
Zebra Danio
Brachydanio rerio
NP_991311
700
78843
T134
V
V
L
P
G
P
P
T
E
S
P
G
M
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649156
598
67364
T110
G
M
P
V
A
L
A
T
Q
A
L
A
K
K
P
Honey Bee
Apis mellifera
XP_392148
633
72356
K110
D
D
E
I
K
N
E
K
T
T
E
A
Q
L
S
Nematode Worm
Caenorhab. elegans
NP_499300
621
71178
E112
K
P
A
E
Q
S
I
E
E
R
L
R
A
K
E
Sea Urchin
Strong. purpuratus
XP_780513
572
64792
A114
P
G
I
P
Q
A
P
A
I
P
K
V
P
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03338
469
55852
N32
L
R
R
E
E
T
T
N
D
E
E
K
F
Q
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
98.6
N.A.
99.5
90.7
N.A.
66.1
94.4
86.3
71.5
N.A.
48.3
52.2
35.8
49.6
Protein Similarity:
100
N.A.
100
98.8
N.A.
99.7
91.9
N.A.
78.9
97.9
93.5
83.8
N.A.
62.9
68.5
55.4
62.5
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
53.3
100
100
80
N.A.
0
6.6
6.6
26.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
73.3
100
100
93.3
N.A.
26.6
26.6
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
8
8
8
0
8
0
15
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% D
% Glu:
58
0
8
15
8
0
8
8
72
8
15
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
15
0
0
58
0
0
0
0
0
0
65
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
58
8
0
0
8
0
8
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
8
0
0
8
0
0
8
8
8
15
0
% K
% Leu:
8
0
8
0
0
8
0
0
0
0
15
0
8
72
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
58
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
0
8
0
0
0
0
0
% N
% Pro:
8
8
8
72
0
65
65
0
0
8
65
0
8
0
8
% P
% Gln:
0
0
0
0
15
0
0
0
8
0
0
0
8
8
0
% Q
% Arg:
0
8
8
0
8
0
0
0
0
8
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
50
0
58
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
8
8
15
8
8
0
0
0
0
72
% T
% Val:
8
58
8
8
0
0
8
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _