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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNL1
All Species:
30.3
Human Site:
S159
Identified Species:
51.28
UniProt:
O43396
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43396
NP_004777.1
289
32251
S159
K
D
T
T
F
L
E
S
D
C
D
E
Q
L
L
Chimpanzee
Pan troglodytes
XP_001137336
285
31851
F156
C
L
R
K
D
T
T
F
L
E
S
D
C
D
E
Rhesus Macaque
Macaca mulatta
XP_001083710
289
32176
S159
K
D
T
T
F
L
E
S
D
C
D
E
Q
L
L
Dog
Lupus familis
XP_541090
267
30276
E138
F
L
E
S
D
C
D
E
Q
L
L
I
T
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDN6
289
32219
S159
K
D
M
S
F
L
E
S
D
C
D
E
Q
L
L
Rat
Rattus norvegicus
Q920J4
289
32231
S159
K
D
L
S
F
L
E
S
D
C
D
E
Q
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510259
342
37565
S212
K
D
P
S
F
L
E
S
D
C
D
E
Q
L
L
Chicken
Gallus gallus
XP_424463
289
32335
S159
K
D
S
T
Y
L
E
S
D
C
D
E
Q
L
L
Frog
Xenopus laevis
NP_001089222
289
32020
S159
K
D
P
T
Y
L
E
S
D
C
D
E
Q
L
L
Zebra Danio
Brachydanio rerio
NP_957432
289
31983
S159
K
D
A
T
Y
L
E
S
D
C
D
E
Q
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523938
287
31709
Q157
A
S
A
G
G
Y
L
Q
S
D
C
D
E
Q
L
Honey Bee
Apis mellifera
XP_623128
287
31633
E157
N
T
D
D
G
Y
L
E
S
E
C
D
E
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786407
287
31919
L157
L
K
K
G
D
S
Y
L
E
S
D
C
D
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SQZ9
176
19652
D47
L
K
Q
G
Y
R
E
D
E
G
L
N
L
E
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
99.6
88.9
N.A.
98.6
98.9
N.A.
77.4
91.6
84
80.6
N.A.
49.8
50.1
N.A.
49.8
Protein Similarity:
100
97.5
99.6
89.9
N.A.
99.3
99.6
N.A.
81.2
96.8
93.4
90.6
N.A.
67.8
66.7
N.A.
68.5
P-Site Identity:
100
0
100
0
N.A.
86.6
86.6
N.A.
86.6
86.6
86.6
86.6
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
6.6
100
20
N.A.
93.3
93.3
N.A.
93.3
100
93.3
93.3
N.A.
20
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
8
0
0
0
0
8
0
0
0
58
15
8
8
0
0
% C
% Asp:
0
58
8
8
22
0
8
8
58
8
65
22
8
8
0
% D
% Glu:
0
0
8
0
0
0
65
15
15
15
0
58
15
15
8
% E
% Phe:
8
0
0
0
36
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
22
15
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
58
15
8
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
15
15
8
0
0
58
15
8
8
8
15
0
8
58
72
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
8
8
0
0
0
58
15
8
% Q
% Arg:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
29
0
8
0
58
15
8
8
0
0
0
8
% S
% Thr:
0
8
15
36
0
8
8
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
29
15
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _